Sökning: "neuroendocrine marker"

Visar resultat 6 - 10 av 27 avhandlingar innehållade orden neuroendocrine marker.

1. 6. Small Intestinal Neuroendocrine Tumours : Genetic and Epigenetic Studies and Novel Serum Biomarkers

   Författare :Katarina Edfeldt; Peter Stålberg; Per Hellman; Gunnar Westin; Malin Sund; Endokrinkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; microarray; tumour suppressor gene; epigenetic; serum biomarkers; Kirurgi; Surgery;

   Sammanfattning : Small intestinal neuroendocrine tumours (SI-NETs) are rare, hormone producing and proliferate slowly. Patients usually display metastases at time of diagnosis, the tumours are difficult to cure, and the disease course is unpredictable. LÄS MER

3. 7. Pancreatic Endocrine Tumors and GIST - Clinical Markers, Epidemiology and Treatment

   Författare :Sara Ekeblad; Britt Skogseid; Peter Stålberg; Barbro Eriksson; Rajesh Thakker; Uppsala universitet; []
   Nyckelord :Medicine; Pancreatic endocrine tumor; Gastrointestinal stromal tumor; Neuroendocrine; Multiple endocrine neoplasia type 1; Prognostic factors; Temozolomide; TNM staging; O6-methylguanine DNA methyltransferase; Growth hormone secretagogue receptor; Ghrelin; Medicin;

   Sammanfattning : Pancreatic endocrine tumors and gastrointestinal stromal tumors are rare. Evidence regarding prognostic factors, and in the former also treatment, is scarce. We evaluated the survival and prognostic factors in a consecutive series of 324 patients with pancreatic endocrine tumors treated at a single institution. LÄS MER

4. 8. Prostate cancer and neuroendocrine differentiation. Molecular aspects in prostate cancer development

   Författare :Nastaran Monsef; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; neuron specific enolase; neuroendocrine differentiation; serotonin; hypoxia; cancer stem cell; synaptophysin; Gleason score; chromogranin A; Gleason grade;

   Sammanfattning : Hormone refractory prostate cancer occurs when androgen-deprivation therapy (ADT) fails to stop the growth of prostate cancer for any longer. Recent studies point towards a role for neuroendocrine (NE) differentiation in the development of hormone refractory disease. LÄS MER

5. 9. CYSTATIN C AND NEUROENDOCRINE DIFFERENTIATION IN THE MALE REPRODUCTIVE SYSTEM AND IN PROSTATE CANCER

   Författare :Thomas Jiborn; Malmö Urologisk cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; androgen deprivation therapy; cysteine protease inhibitor; neuroendocrine differentiation; cysteine protease; male reproductive tract; prostate cancer; nefrologi; Urologi; nephrology;

   Sammanfattning : Cystatins are endogenous protease inhibitors that regulate the proteolytic activities of family C1 (papain-like) cysteine proteases, such as human cathepsins B, H, K, L, and S. Cystatin C shows the fastest inhibition and the highest affinity of all cystatins towards lysosomal cysteine proteases in general and is widespread in human tissues and body fluids. LÄS MER

7. 10. Neuroendocrine tumors of the digestive system : Modulation of apoptosis and factors associated with growth regulation during biotherapies

   Författare :S. A. Hassan Imam; Uppsala universitet; []
   Nyckelord :Medical sciences; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Neuroendocrine tumors of the gut have the potential to create life-threatening syndromes which become difficult to treat. Tumor mass reduction, by medical therapy, is one of the choices of treatments. LÄS MER