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Visar resultat 1 - 5 av 27 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Neuroendocrine Stress Response after Burn Trauma

   Författare :Andreas Lindahl; Bengt Gerdin; Lisa Ekselius; Kristofer Rubin; Riddez Louis; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Burn; Injuries; Neuroendocrine; Intensive Care; Cortisol; Chromogranin A; Natriuretic peptides; Plastikkirurgi; Plastic Surgery;

   Sammanfattning : Some aspects of the stress response during acute intensive care for severe burns are described and quantified by measuring hormonal and neuroendocrine patterns and relating these to organ function in the short term. This includes an assessment of whether there are markers for the severity of stress that are better than conventional descriptors of the severity of a burn in predicting failing organ function. LÄS MER

3. 2. Expression of Neuroendocrine Markers in Normal and Neoplastic Tissue with an Emphasis on Ghrelin and Obestatin

   Författare :Malin Grönberg; Eva Tiensuu Janson; Apostolos Tsolakis; Jan Saras; Mauro Papotti; Uppsala universitet; []
   Nyckelord :ghrelin; obestatin; neuroendocrine marker; immunohistochemistry; neuroendocrine tumors; breast cancer; mammary glands; MEDICINE; MEDICIN; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

   Sammanfattning : The aim of this thesis was to characterize the expression of the peptides ghrelin and obestatin, as well as other neuroendocrine markers in human normal tissues, in invasive breast cancer and a wide panel of neuroendocrine tumors (NETs). In normal tissues the expression of ghrelin and obestatin was mainly localized to the gastric mucosa, and in lesser extent in the remaining gastrointestinal tract, endocrine pancreas and mammary glands. LÄS MER

4. 3. Theranostics in Neuroendocrine Tumors : Somatostatin Receptor Imaging and Therapy

   Författare :Ezgi Ilan; Mark Lubberink; Peter Bernhardt; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; 68Ga-DOTATATE; 68Ga-DOTATOC; PRRT; Theranostics; PET CT; SPECT CT; Neuroendocrine tumors; Somatostatin receptors; Medicinsk radiofysik; Medical Radiophysics;

   Sammanfattning : Neuroendocrine tumors (NETs) are characterized by cellular overexpression of somatostatin receptors (SSTR), which allows for the use of radiolabeled somatostatin analogs (SSA) for both imaging and therapy. Because NETs often are diagnosed at a metastatic stage, curative surgery is not possible. LÄS MER

5. 4. Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours

   Författare :Christina Swärd; Göteborgs universitet; []
   Nyckelord :Carcinoid; Endocrine pancreatic tumour; Neuroendocrine; Octreotide; Somatostatin receptor; Peptide receptor; Radionuclide therapy; Absorbed dose; Chromogranin A; Liver transplantation;

   Sammanfattning : Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours Background. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) originate from endocrine cells of the intestinal mucosa and pancreas. LÄS MER

7. 5. Oncolytic Adenovirus Therapy of Neuroendocrine Tumors

   Författare :Justyna Leja; Magnus Essand; Valeria Giandomenico; Akseli Hemminki; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adenovirus; virotherapy; oncolytic virus; neuroendocrine tumors; chromogranin A; somatostatin receptors; microRNA; novel biomarkers; Molecular biology; Molekylärbiologi; Oncology; Onkologi; Virology; Virologi; Tumour biology; Tumörbiologi; Medical Science; Medicinsk vetenskap; Oncology; Onkologi; Medical Virology; Medicinsk virologi; Molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : Neuroendocrine tumors (NETs), originally described as carcinoids, represent a rare and heterogeneous group of neoplasms associated with intensive secretion of hormones, bioactive peptides and amines. Most of the patients are diagnosed at a late stage of disease, often with liver metastases. LÄS MER