Sökning: "neointimal hyperplasia"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden neointimal hyperplasia.
1. Cardiovascular role of PDGF-B in development and disease. Studies in genetically engineered mice
Sammanfattning : Platelet-derived growth factor B (PDGF-B) is vital for microvascular development, and retention of PDGF-B to extracellular matrix (ECM) is important in this process. However, the role and source of PDGF-B in development of macrovascular function is disputed. LÄS MER
2. Tumor Necrosis Factor-alpha as a target cytokine in vascular disease
Sammanfattning : Inflammation plays an important role in atherosclerosis. One of the most potent pro-inflammatory cytokines is tumor necrosis factor-alpha (TNF-a), a cytokine identified to have a pathogenic role in chronic inflammatory diseases such as rheumatoid arthritis (RA). LÄS MER
3. Developmental origin and molecular regulation of vascular smooth muscle cells
Sammanfattning : Several pathologies of the vascular system have been suggested to be dependent on the smooth muscle cells (SMCs) that build up the vessel wall. Aortic SMCs have been proposed to derive from lateral plate mesoderm. LÄS MER
4. The role of the adventitia and perivascular tissue for the formation of intimal hyperplasia
Sammanfattning : Symptomatic atherosclerosis is commonly treated with balloon angioplasty or bypass surgery. About 30% of the interventions will re-narrow within a year due to restenosis and graft-stenosis. Thickening of the luminal layer, the intima, is an important component in these side-effects. LÄS MER
5. Mechanisms of thrombosis and restenosis after vascular injury
Sammanfattning : Atherosclerosis is the underlying cause of about 50% of all deaths in the western world. Peripheral vascular disease commonly affects the arteries supplying the leg and is mostly caused by atherosclerosis. LÄS MER