Sökning: "DCE-MRI"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet DCE-MRI.

  1. 1. Cerebral arterial pulsatility imaging using 4D flow MRI : methodological development and applications in brain aging

    Författare :Tomas Vikner; Anders Wåhlin; Anders Eklund; Jan Malm; Lars Nyberg; Susanne Schnell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; 4D flow MRI; medical image analysis; cerebral hemodynamics; arterial pulsatility; DCE MRI; blood-brain barrier; white matter lesions; perivascular spaces; cerebral small vessel disease; hippocampus; cognition; aging; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Sammanfattning : 4D flow magnetic resonance imaging (MRI) is increasingly recognizedas a versatile tool to assess arterial and venous hemodynamics. Cerebral arterial pulsatility is typically assessed by analyzing flow waveforms over the cardiac cycle, where flow amplitude is a function of cardiac output, central arterial stiffness, and cerebrovascular resistance and compliance. LÄS MER

  3. 2. Quantitative Evaluation of Contrast Agent Dynamics in Liver MRI

    Författare :Nils Dahlström; Örjan Smedby; Torkel Brismar; Anders Ynnerman; Carsten Thomsen; Linköpings universitet; []
    Nyckelord :Liver; spleen; hepatobiliary system; liver function; MRI; DCE-MRI; Gd-EOBDTPA; Gd-BOPTA; pharmacokinetic; hepatocyte; relaxivity.; MEDICINE; MEDICIN;

    Sammanfattning : The studies presented here evaluate the biliary, parenchymal and vascular enhancement effects of two T1-shortening liver-specific contrast agents, Gd-BOPTA and Gd-EOB-DTPA, in Magnetic Resonance Imaging (MRI) of healthy subjects and of patients.Ten healthy volunteers were examined with both contrast agents in a 1. LÄS MER

  4. 3. Contributions to quantitative dynamic contrast-enhanced MRI

    Författare :Anders Garpebring; Mikael Karlsson; Ronnie Wirestam; Nils Östlund; Jón Hauksson; Steven Sourbron; Umeå universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Dynamic contrast-enhanced MRI; quantitative imaging; parameter estimation; uncertainty estimation; arterial input function; radiofysik; radiation physics;

    Sammanfattning : Background: Dynamic contrast-enhanced MRI (DCE-MRI) has the potential to produce images of physiological quantities such as blood flow, blood vessel volume fraction, and blood vessel permeability. Such information is highly valuable, e.g., in oncology. LÄS MER

  5. 4. Perfusion MRI of the brain after radiotherapy in patients with glioblastoma – potential and problems

    Författare :Markus Fahlström; Elna-Marie Larsson; Tufve Nyholm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Perfusion Magnetic Resonance Imaging (MRI) is a useful tool in diagnostic evaluation and treatment response assessment in patients with glioblastoma. The standard treatment regimen includes surgical resection, radiotherapy and adjuvant chemotherapy. However, prognosis is poor; relative 5-year survival is 3–5%. LÄS MER

  7. 5. On potentials and limitations of perfusion MRI in neurological disorders

    Författare :Markus Fahlström; Mark Lubberink; Adam Espe Hansen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurological disease; MRI; Perfusion; 15O-water PET; Medicinsk radiofysik; Medical Radiophysics;

    Sammanfattning : Cerebral perfusion outlines several parameters which describe the status of cerebral haemodynamics. Numerous neurological diseases affect cerebral perfusion, thus the importance of diagnostic measurements. LÄS MER