Sökning: "epithelioid"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet epithelioid.

  1. 1. Tumor Necrosis Factor-alpha as a target cytokine in vascular disease

    Författare :Lena Brånén; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; cell replication; Cardiovascular system; Kardiovaskulära systemet; spindle-shaped; epithelioid; smooth muscle cells; periadventitial cuff injury; sTNF-R1; bone marrow transplantation; chimeric fusion protein; atherogenic diet; ApoE; TNF-a; genetically altered mice; en face preparation; atherosclerosis; neointimal hyperplasia;

    Sammanfattning : Inflammation plays an important role in atherosclerosis. One of the most potent pro-inflammatory cytokines is tumor necrosis factor-alpha (TNF-a), a cytokine identified to have a pathogenic role in chronic inflammatory diseases such as rheumatoid arthritis (RA). LÄS MER

  3. 2. Electron Microscopy in Diagnostic Pathology with Reference to Mesenchymal Tumors

    Författare :Birgitta Carlén; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; synovial sarcoma; Kaposi´s sarcoma; epithelioid sarcoma; parachordoma; alveolar soft part sarcoma; small cell malignant tumors of childhood and adolescence; cultured cells; surgical specimens; Transmission electron microscopy; fine needle aspiration; General pathology; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Sammanfattning : The experience acquired over a period of 15 years of diagnostic electron microscopy of fine needle aspirates and surgical specimens constitutes the base for this thesis. Some of the tumors analyzed represent rare soft tissue tumors, and consequently not very often ultrastructurally described. LÄS MER

  4. 3. Studies on mesothelial differentiation : prognostic and therapeutic approaches to malignant mesothelioma

    Författare :Xiaojuan Sun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mesothelium; Differentiation; Malignant Mesothelioma; Proteasome; Selenium; Thioredoxin;

    Sammanfattning : Malignant mesothelioma (MM), a tumor with a poor prognosis, causes the death of most patients within a year of diagnosis since various treatments seem to have little effect on its outcome. The biological behavior of MM varies greatly, and this heterogeneity is related to its morphology, which may be epithelioid, sarcomatoid (fibroblastoid) or biphasic, the sarcomatoid phenotype being associated with a shorter survival. LÄS MER

  5. 4. Mesothelial differentiation, mesothelioma and tumor markers in serous cavities

    Författare :Miklós Gulyás; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mesothelium; mesothelioma; differentiation; differential gene expression; proteoglycans; tumor markers; effusion;

    Sammanfattning : Mesothelial cells covering the serous membranes are of mesodermal origin although they acquire several characteristics of epithelial cells. The cytological and histological diagnosis of malignant tumors in serous cavities is sometimes a major challenge: the main diagnostic alternatives are reactive benign mesothelium, mesothelioma and adenocarcinoma. LÄS MER

  7. 5. Genomic and Transcriptomic Analyses of Osteogenic Tumours of Bone

    Författare :Karim Saba; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Primary tumours of bone are heterogenous and infrequent neoplasms. Distinguishing between benign, intermediate and malignant entities can in some instances pose a clinical challenge. For some tumour types, there is still much to be learned about the genetic mechanisms that give rise to and drive these tumours forward. LÄS MER