Sökning: "microglia"

Visar resultat 21 - 25 av 170 avhandlingar innehållade ordet microglia.

1. 21. Role of Neuroinflammation in Parkinson's Disease and Related Disorders

   Författare :Edoardo Brandi; Neural plasticitet och reparation; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha synuclein; Preformed fibrils; Microglia; Astrocyte; Neuroinflammation; Lipopolysaccharides; Parkinson Disease; Lewy Body Dementia; Multiple system atrophy; Synucleinopathies;

   Sammanfattning : Synucleinopathies are neurodegenerative disorders characterized by intracellular protein aggregates, progressive neurodegeneration, and neuroinflammation. Alpha-synuclein (a-syn) is the principal component of intracellular aggregates and can be modified by several mutations and post-translational modifications (PTMs), which can alter the protein structure affecting its aggregation, toxicity, and ability to spread. LÄS MER

3. 22. The Role of miRNA in Neurogenesis and Cell Specification

   Författare :Malin Åkerblom; Molekylär neurogenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; microRNA; miR-124; miR-9; miR-125; adult neurogenesis; neural stem cells; cell specification; microglia; lentiviral vectors; olfactory bulb; olfactory bulb interneurons;

   Sammanfattning : Only a few decades ago, it was generally believed that gene expression was controlled in a unidirectional way, i.e. DNA was transcribed into RNA, which simply acted as a messenger molecule used to produce the protein that executed cellular functions. LÄS MER

4. 23. Perinatal Staphylococcus epidermidis infection and the immature brain: a neuroinflammatory link

   Författare :Giacomo Gravina; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S. epidermidis; neonatal brain injury; hypoxia-ischemia; microglia; neuroinflammation; S. epidermidis; neonatal brain injury; hypoxia-ischemia; microglia; neuroinflammation;

   Sammanfattning : Preterm birth and its associated complications are among the most serious global health issues that modern society faces. Due to the prolonged medical care and immature immune system, preterm infants have a higher susceptibility to infections, which puts them at a higher risk of developing neurological impairments as well as neurodevelopmental diseases. LÄS MER

5. 24. Inflammatory response in the immature brainafter hypoxia-ischemia. Application of microarray and transgenic technology

   Författare :Maj Hedtjärn; Göteborgs universitet; []
   Nyckelord :hypoxia-ischemia; neonatal; brain; inflammation; cytokine; IL-1; IL-18; microglia; ; gene; microarray;

   Sammanfattning : Hypoxic-ischemic (HI) brain injury remains a common problem encountered during theneonatal period, and it is a major cause of perinatal mortality and long term neurologicalimpairments. After HI, an inflammatory reaction is elicited in the brain, which is believedto contribute to the secondary progression of brain injury. LÄS MER

7. 25. Immune responses and synaptic protein expression in epilepsy

   Författare :Una Avdic; Epilepsicentrum; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epilepsy; non-convulsive status epileptics; synaptic proteins; immune response; microglia; inflammation;

   Sammanfattning : .... LÄS MER