Sökning: "Epilepsicentrum"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet Epilepsicentrum.
1. Chemogenetics, Induced Neurons and Pluripotent Stem Cells: Towards Advanced Gene and Cell Therapies Targeting Epilepsy
Sammanfattning : The complexity of the central nervous system and existence of the blood-brain barrier often causes difficulties for traditional pharmacological treatments of neurological diseases. This thesis explores the feasibility and potential for novel gene and cell therapy approaches, which hold better promise for neurological disorders, while particularly targeting epilepsy. LÄS MER
2. Immune responses and synaptic protein expression in epilepsy
Sammanfattning : .... LÄS MER
3. Novel approaches to explore mechanisms of epileptic seizures - optogenetic and chemogenetic manipulation of hippocampal circuitry
Sammanfattning : Epilepsy comprises a family of neurological disorders characterized by recurrent seizures, which can be highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmaceuticals. LÄS MER
4. Enhancing neuronal inhibition by cell and gene therapy as a novel treatment for Epilepsy
Sammanfattning : Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people worldwide of all ages and genders. LÄS MER
5. Advancing gene therapy for epilepsy. Translational pre-clinical studies with neuropeptide Y and glial cell-line derived neurotrophic factor
Sammanfattning : Epilepsy is a neurological disorder, affecting approximately 1% of the population. The high rate of drug-resistance in epilepsy in general (30%), and temporal lobe epilepsy (TLE) in particular, pose a serious clinical problem. Thus, novel treatments for drug-resistant epilepsy is highly warranted. LÄS MER
