Sökning: "microglia"

Visar resultat 16 - 20 av 170 avhandlingar innehållade ordet microglia.

  1. 16. Reactive gliosis in the injured brain: The effect of cell communication and Nrf2-mediated cellular defence

    Författare :Heléne Andersson; Göteborgs universitet; []
    Nyckelord :Keywords: astrocyte; gap junction; Hmox1; microglia; Nrf2; Nqo1; oxidative stress; reactive gliosis;

    Sammanfattning : Stroke and other brain injuries trigger an extensive glial cell response referred to as reactive gliosis. Reactive gliosis is characterized by hypertrophic and proliferating astrocytes, proliferating microglia and NG2-positive cells, which eventually form a bordering glial scar around the damaged area. LÄS MER

  3. 17. Brain Inflammation and Adult Hippocampal Neurogenesis in Epilepsy

    Författare :Deepti Chugh; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; Inflammation; Neurogenesis; Hippocampus; Microglia; Adhesion molecules; Scaffolding proteins;

    Sammanfattning : Epilepsy is a severe chronic neurological disorder characterized by recurrent spontaneous seizures. Excitatory/inhibitory (E/I) imbalance, neuronal loss, brain inflammation, and altered adult neurogenesis are some of the characteristic hallmarks of epilepsy. LÄS MER

  4. 18. Characterizing and modulating the effects of ionizing radiation to the juvenile hippocampus

    Författare :Malin Blomstrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; low-dose radiation; CNS; hippocampus; apoptosis; cytokines; growth factors; microglia; medulloblastoma; hippocampal sparing; tumor bed boost; cognitive risk estimation;

    Sammanfattning : Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with late side effects e.g. LÄS MER

  5. 19. Effects of gold- and silver nanoparticles on the retina

    Författare :Patrik Maximilian Bauer; Funktionell zoologi; []
    Nyckelord :Microglia; Retina; In vitro; Nanoparticles;

    Sammanfattning : Over the past decade, a massive increase in the use of nanomaterials and nanoparticles (NPs) in both commercial and medical applications has occurred. Medical applications include advanced drug delivery vehicles, imaging and hyper thermic therapies. LÄS MER

  7. 20. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells

    Författare :Malin Samuelsson; Kerstin Iverfeldt; Piet Eikelenboom; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; amyloid-β; astrocytes; C EBP; glia; microglia; neuroinflammation; NF-кB; Neurochemistry; Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. LÄS MER