Sökning: "Lipopolysaccharides"
Visar resultat 1 - 5 av 38 avhandlingar innehållade ordet Lipopolysaccharides.
1. Mixed Effects Modelling and Optimal Design of TNFα Response in LPS Challenge Studies - Methods and Applications in Drug Discovery
Sammanfattning : ''Endotoxin and mycoplasma are Nature’s darkest secrets. If they are ever solved, Hell itself will open.'' - Lewis Thomas* Endotoxin, or lipopolysaccharides (LPS), are heterogeneous components from the cell wall of Gram-Negative bacteria and a common challenger in the field of drug discovery. LÄS MER
2. Exploring the structure of oligo- and polysaccharides : Synthesis and NMR spectroscopy studies
Sammanfattning : A deeper understanding of the diversity of carbohydrates and the many applications of oligo- and polysaccharides found in nature are of high interest. Many of the processes involving carbohydrates affect our everyday life. This thesis is based on six papers all contributing to an extended perspective of carbohydrate property and functionality. LÄS MER
3. Monoclonal antibodies against Haemophilus lipopolysaccharides
Sammanfattning : The genus Haemophilus comprises a group of gram-negative bacteria with fastidious growth requirements. Among the Haemophilus species, H. influenzae and H. ducreyi are the most important in human medicine. LÄS MER
4. Role of Neuroinflammation in Parkinson's Disease and Related Disorders
Sammanfattning : Synucleinopathies are neurodegenerative disorders characterized by intracellular protein aggregates, progressive neurodegeneration, and neuroinflammation. Alpha-synuclein (a-syn) is the principal component of intracellular aggregates and can be modified by several mutations and post-translational modifications (PTMs), which can alter the protein structure affecting its aggregation, toxicity, and ability to spread. LÄS MER
5. Studies on some Salmonella lipopolysaccharides
Sammanfattning : .... LÄS MER