Sökning: "luciferase"

Visar resultat 11 - 15 av 92 avhandlingar innehållade ordet luciferase.

  1. 11. Molecular studies of the hepatitis C virus : the role of IRES activity for therapy response, and the impact of the non-structural protein

    Författare :Hannah Kim Lindström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hepatitis C virus; IRES; viral translation; dual luciferase assay; therapy response; NS4B; topology; membrane rearrangements; membrane associated foci; Immunofluorescence; oligomerization; viral replication; bi-cistronic subgenomic replicon; replicon complex; mutations;

    Sammanfattning : Chronic hepatitis C can lead to life threatening conditions like cirrhosis, liver failure and hepatocellular carcinoma. There are an estimated 170 million chronic carriers of the hepatitis C virus (HCV) world wide, making it a serious global health problem. LÄS MER

  3. 12. The interactome of the Epstein-Barr virus nuclear antigen 5 suggests novel roles in RNA and protein metabolism

    Författare :Josefine Ekholm; Göteborgs universitet; []
    Nyckelord :Epstein-Barr virus; EBNA5; chaperone; proteasome; nucleolus;

    Sammanfattning : Epstein-Barr virus (EBV) is a human herpes virus that infects B and epithelial cells of the oropharynx. EBV is transmitted by saliva and establishes a lifelong latency in over 90% of the world's population. During latency, the virus exists predominantly as multicopy episomes in the nuclei of memory B cells. LÄS MER

  4. 13. Quantitative monitoring of microorganisms in environmental samples using biomarkers

    Författare :Annelie Elväng; James Prosser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : The use of microorganisms in environmental biotechnology is an area of growing interest. Microorganisms have been used for diverse applications, such as biological fertilizers, biological pesticides and bioremediation of toxic chemicals. In many cases, the bacteria of interest have been genetically alterred to improve certain traits. LÄS MER

  5. 14. Pyrosequencing

    Författare :Samer Karamohamed; KTH; []
    Nyckelord :;

    Sammanfattning : Pyrosequencing is a method that can be used in almost allDNA sequencing applications. The method uses coupled reactionsof ATP sulfurylase and firefly luciferase to monitor theinorganic pyrophosphate (PPi) released during nucleotideincorporation onto a DNA primer. LÄS MER

  7. 15. Post-Transcriptional Regulation of the Murine Inducible Nitric Oxide Synthase Gene

    Författare :Malin Söderberg; Matti A. Lang; Françoise Raffalli-Mathieu; Eeva Moilanen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; iNOS; inducible nitric oxide synthase; gene regulation; post-transcriptional; mRNA stability; RNA-protein interactions; dexamethasone; murine; heterogeneous nuclear ribonucleoprotein; hnRNPI; hnRNPL; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Sammanfattning : Large amounts of nitric oxide (NO) are produced by the inducible nitric oxide synthase (iNOS) upon inflammatory stimuli. NO is a multifaceted molecule, which may have beneficial effects as an antimicrobial agent in the immune defense, or cytotoxic effects in chronic inflammations, manifested as e.g. arthritis and asthma. LÄS MER