Sökning: "replicon complex"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden replicon complex.
1. Molecular studies of the hepatitis C virus : the role of IRES activity for therapy response, and the impact of the non-structural protein
Sammanfattning : Chronic hepatitis C can lead to life threatening conditions like cirrhosis, liver failure and hepatocellular carcinoma. There are an estimated 170 million chronic carriers of the hepatitis C virus (HCV) world wide, making it a serious global health problem. LÄS MER
2. Topology and membrane rearrangements of the hepatitis C virus protein NS4B
Sammanfattning : Hepatitis C virus (HCV) is a major cause of chronic liver disease and viral hepatitis around the world. Approximately 180 million people or 3% of the world's population are infected with the virus. LÄS MER
3. Structural and functional studies on ribonucleotide reductase protein B2 from Escherichia coli
Sammanfattning : Ribonucleotide reductase catalyzes the reduction of ribonucleotidesto the corresponding deoxyribonucleotides, the building blocks forDNA. The enzyme from Escherichia coli consists of two proteins.Bl and B2. Protein B2 contains two dinuclear iron centers and astable tyrosyl radical. LÄS MER
4. Molecular characterization of the Tick-borne encephalitis virus : Environments and replication
Sammanfattning : The flavivirus genus is of major concern for world morbidity and mortality and includes viruses causing both encephalitic as well as hemorrhagic diseases. The incidence of Tick-borne encephalitis is increasing in many European countries and several reports have emphasized the expansion of the main vector, Ixodes ricinus. LÄS MER
5. Co-operative recombination mechanisms promoting gene clustering and lateral transfer of antibacterial drug resistance
Sammanfattning : Transposons of the Mu superfamily are widespread and have been shown to play an important role in the dissemination of antibiotic resistance among microorganisms. One of these elements, Tn5090/Tn402 is the basal vehicle of the type 1 integrons in which mobile resistance gene cassettes are inserted to form clusters and operons. LÄS MER