Sökning: "nucleolin"

Hittade 3 avhandlingar innehållade ordet nucleolin.

  1. 1. The role of non-coding single-stranded oligonucleotides on Respiratory syncytial virus infection

    Författare :Sandra Axberg Pålsson; Anna-Lena Spetz; Annika Karlsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Respiratory syncytial virus RSV ; single-stranded oligonucleotide ssON ; small non-coding RNA sncRNA ; nucleolin; virus infection; antiviral; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Respiratory syncytial virus (RSV) is an enveloped RNA virus of the Pneumoviridae family. RSV is reported to infect host cells by receptor-mediated endocytosis, also called clathrin-dependent endocytosis. Many reports indicate that the virus utilizes the host receptor nucleolin for entry. LÄS MER

  3. 2. Harnessing the immunoregulatory capacity of single-stranded oligonucleotides to modulate innate immunity

    Författare :Aleksandra Dondalska; Anna-Lena Spetz; Jenny Hallgren Martinsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; single-stranded oligonucleotides; Toll-like receptors; influenza; respiratory syncytial virus; dendritic cell; mast cell; virus infection; inflammation; itch; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : As the first line of defense, the innate immune system is exceptionally efficacious against invading pathogens but must be tightly regulated to avoid immune-related pathogenesis. Accordingly, the innate immune system recognizes highly conserved components associated with infections and damaged cells using a limited number of pattern-recognition receptors (PRRs), which are differentially expressed across cell types. LÄS MER

  4. 3. Molecular structure and intracellular location of five RNA : associated proteins in the salivary glands of the dipteran Chironomus tentans

    Författare :Sun Xin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :hnRNPs; RNA-binding domains; shuttling proteins; non-shuttling proteins; nucleo-cytoplasmic transport; SR proteins;

    Sammanfattning : The structure and intracellular flow of specific RNA-associated proteins have been characterized in the salivary gland cells in the dipteran Chironomus tentans. These cells contain four polytene chromosomes (I-IV), two of which harbour a nucleolus. LÄS MER