Sökning: "in vitro angiogenesis assay"

Visar resultat 6 - 10 av 20 avhandlingar innehållade orden in vitro angiogenesis assay.

1. 6. Development and optimization of a 3D in vitro model for osteogenic biomaterial evaluation

   Författare :Luis Oliveros Anerillas; Peyman Kelk; Paul J. Kingham; Mikko Lammi; Jöns Hilborn; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; angiogenesis; biomaterial; bone marrow mesenchymal stem cells; bone regeneration; hydrogel; osteoinduction; osteogenesis; scaffold; type I collagen; 3D culture; biology; biologi; biomedical laboratory science; biomedicinsk laboratorievetenskap; Medical Cell Biology; medicinsk cellbiologi;

   Sammanfattning : Despite the innate regenerative capabilities of bone tissue, self-repair is impaired when an injury exceeds the critical size threshold because of trauma, congenital, or pathological conditions. Autologous transplantation is the gold standard to reconstruct large bone defects. LÄS MER

3. 7. Regulators of angiogenesis in diabetes and tumors

   Författare :Sergiu-Bogdan Catrina; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Diabetes; HIF; hypoxia; tumors; growth factors; wound healing;

   Sammanfattning : Angiogenesis is tightly regulated in order to provide adequate supply of nutrients and oxygen for normal cellular function. Tissue oxygenation represents a balance between the requirement for oxygen to maintain the cellular energy level and the potential risk of cellular oxidative damage. LÄS MER

4. 8. In vitro wound healing characteristics of amelogenins

   Författare :Sofia Almqvist; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amelogenins; extracellular matrix; cell culture; macrophage; fibroblast; endothelial cell; integrin; cytokine; inflammation; wound healing tissue repair;

   Sammanfattning : Wound healing involves the co-ordinated actions of several cell types, soluble cell mediators and extracellular matrix (ECM). This research project intended to investigate the role of certain ECM proteins in different processes during tissue repair by studying the interaction between dermal cells and ECM. LÄS MER

5. 9. Application of a New Logic to Old Drugs: Angiogenesis Inhibition in Neuroblastoma

   Författare :Åsa Svensson; Rolf Christofferson; Per Kogner; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; angiogenesis; neuroblastoma; CHS 828; digoxin; combination treatment; Cellbiologi; Cell biology; Cellbiologi; Medical Cell Biology; medicinsk cellbiologi;

   Sammanfattning : Neuroblastoma is one of the most common solid cancers of early childhood. In Sweden, approximately 10-15 cases occur annually. The overall five-year neuroblastoma survival in Europe is approximately 45%. Since cancer treatment involves drugs with risks of side effects in the growing child, there is a need for more effective and less toxic drugs. LÄS MER

7. 10. Angiostatic mechanisms of endogenous angiogenesis inhibitors

   Författare :Niina Veitonmäki; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Angiogenesis; tumor growth; angiostatin; K 1 - 5; adiponectin; hTERT; p16;

   Sammanfattning : Angiogenesis, the process of sprouting of new capillaries from the existing blood vessels, is essential for tumor growth and metastasis. Angiostatin was discovered as the first specific endogenous angiogenesis inhibitor nearly 10 years ago. The structure of angiostatin consists of the first three/four kringle (K1-3/K1-4) domains of plasminogen. LÄS MER