Sökning: "Rolf Christofferson"

Hittade 5 avhandlingar innehållade orden Rolf Christofferson.

  1. 1. Angiogenesis as induced by trophoblast and cancer cells

    Författare :Rolf H. Christofferson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Treatment of Experimental Neuroblastoma with Angiogenic Inhibitors

    Författare :Ulrika Bäckman; Rolf Christofferson; Sven Påhlman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Angiogenesis; Neuroblastoma; MYCN; VEGF; SU11657; SU5416; TNP-470; zoledronic acid; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Neuroblastoma is a childhood cancer that originates from neuroblasts in the peripheral nervous system. Neuroblastoma show considerable heterogeneity with respect to location, responsiveness to treatment and prognosis. LÄS MER

  4. 3. Novel Treatment Modalities for High-Risk Neuroblastoma : Studies in Animal Models

    Författare :Dieter Fuchs; Faranak Azarbayjani; Rolf Christofferson; Sven Påhlman; Uppsala universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; neuroblastoma; bevacizumab; SU11248; GMX1778; GMX1777; animal model; Medicine; Medicin;

    Sammanfattning : Neuroblastoma, the most common extracranial solid tumor of childhood, is a heterogeneous tumor. In some patients, the tumor can go into spontaneous regression and disappear whereas other patients have rapidly growing tumors with a poor prognosis. LÄS MER

  5. 4. Angiogenesis in childhood malignancies

    Författare :Erik Sköldenberg; Rolf Christofferson; Göran Läckgren; Agneta Nordenskjöld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Angiogenesis Factor; Biopsy; Needle; Neovascularization; Pathologic; Nephroblastoma; Reference value; Kirurgi; Surgery; Kirurgi; Pediatric Surgery; kirurgi; särskilt barnkirurgi;

    Sammanfattning : Angiogenesis is necessary for the growth and spread of solid tumors. In these studies angiogenesis was measured in childhood malignancies in general and in Wilms’ tumor in particular, and cutting needle biopsy (CNB) specimens were evaluated for diagnosis in childhood renal tumors. LÄS MER

  7. 5. Application of a New Logic to Old Drugs: Angiogenesis Inhibition in Neuroblastoma

    Författare :Åsa Svensson; Rolf Christofferson; Per Kogner; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; angiogenesis; neuroblastoma; CHS 828; digoxin; combination treatment; Cellbiologi; Cell biology; Cellbiologi; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : Neuroblastoma is one of the most common solid cancers of early childhood. In Sweden, approximately 10-15 cases occur annually. The overall five-year neuroblastoma survival in Europe is approximately 45%. Since cancer treatment involves drugs with risks of side effects in the growing child, there is a need for more effective and less toxic drugs. LÄS MER