Sökning: "immune system evolution"

Visar resultat 11 - 15 av 76 avhandlingar innehållade orden immune system evolution.

  1. 11. Innate immune mechanisms of atherosclerosis

    Författare :Xintong Jiang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is a multi-factorial immune mediated disease in arterial wall characterized by lipid driven inflammation through activation of the immune system. Chronic vascular inflammation is an important component that modulates atherosclerosis evolution and its complications. LÄS MER

  3. 12. Immunoecology of the Great Snipe (Gallinago media) : Mate Choice, MHC Variation, and Humoral Immunocompetence in a Lekking Bird

    Författare :Robert Ekblom; Jacob Höglund; Mats Grahn; Scott V. Edwards; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Behaviour; Major histocompatibility complex class II B; Sexual selection; Evolution; Leks; Biologi; Biology; Biologi;

    Sammanfattning : At the centre of the vertebrate immune system is a group of proteins called MHC (major histocompatibility complex) molecules. These function in self – non self recognition and activation of the immune defence against intruding parasites and pathogens. LÄS MER

  4. 13. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors

    Författare :Anders Bengtsson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; Risk factors; Human parvovirus B19; Immune complex; Disease activity; Interferon-alpha; SLE; Retrovirus;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). LÄS MER

  5. 14. Antibody Evolution and Repertoire Development

    Författare :Johan Lantto; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; virus neutralization; trinucleotide repeat; insertion; immunoglobulin variable genes; human cytomegalovirus; glycoprotein B; deletion; antibody; antibody repertoire;

    Sammanfattning : Antibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. LÄS MER

  7. 15. Gene conversion of the mouse MHC class II

    Författare :Kari Högstrand; Ulf Gyllensten; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC; H2; gene conversion; evolution; polymorphism; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : The major histocompatibility complex (MHC) is the most polymorphic vertebrate gene loci known to exist. Gene products of the MHC are responsible for presentation of antigen derived peptides to T cells of the immune system, which thereby become activated and involved in the elimination of particles recognised as non-self. LÄS MER