Sökning: "human cytomegalovirus"

Visar resultat 1 - 5 av 51 avhandlingar innehållade orden human cytomegalovirus.

  1. 1. Cellular Immune Responses to Cytomegalovirus

    Författare :Anna Karin Lidehäll; Olle Korsgren; Thomas Tötterman; Ineke ten Berge; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytomegalovirus; cellular immunology; infection; immune responses; congenital infection; CD4 T cells; CD8 T cells; immunosuppressed; Clinical immunology; Klinisk immunologi;

    Sammanfattning : Cytomegalovirus (CMV) is a widespread infection affecting 50-90% of the human population. A typical silent primary infection is followed by life-long persistence in the host under control by virus-specific CD8 (“killer”) and CD4 (“helper”) T cells. LÄS MER

  3. 2. Human cytomegalovirus immune evasion strategies

    Författare :Jenny Odeberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Human cytomegalovirus (HCMV) is a member of the herpes virus family. HCMV is a ubiquitous pathogen, causing severe morbidity and mortality in immunocompromised patients, and is a major factor in congenital birth defects. LÄS MER

  4. 3. Cytomegalovirus Infection in Immunocompetent and Renal Transplant Patients : Clinical Aspects and T-cell Specific Immunity

    Författare :Fredrik Sund; Britt-Marie Eriksson; Olle Korsgren; Halvor Rollag; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytomegalovirus; renal transplantation; cellular immunity; valacyclovir; mismatched; prophylaxis; tetramer; CD4 T cells; CD8 T cells; Infectious diseases; Infektionssjukdomar;

    Sammanfattning : Cytomegalovirus (CMV) is a β-herpesvirus that, after primary infection, establishes a life-long persistence in the human host. Up to 90% of humans are infected with CMV, that is kept under control by CMV-specific CD8+ and CD4+ T cells. In patients with an impaired cellular immunity, however, CMV infections can be life-threatening. LÄS MER

  5. 4. Towards understanding of Human Cytomegalovirus in Glioblastoma

    Författare :Olesja Fornara; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Human Cytomegalovirus (HCMV) is a widely prevalent herpesvirus. Following an active primary infection, often asymptomatic or subclinical in immunocompetent individuals, the virus establishes latency. LÄS MER

  7. 5. Herpesvirus infections in transplant recipients

    Författare :Jenny K Lindahl; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allogeneic stem cell transplantation; Cytomegalovirus; Epstein-Barr virus; Human Herpesvirus type 6; Renal transplantation; Varicella zoster virus;

    Sammanfattning : Abstract Herpesvirus infections are common and can cause serious and life-threatening conditions in transplanted individuals. In this thesis, consisting of 4 papers (I-IV), we investigated primary infection and reactivation of Cytomegalovirus (CMV), Human Herpesvirus type 6 (HHV-6), Varicella Zoster Virus (VZV) and Epstein-Barr Virus (EBV) in transplant patients. LÄS MER