Sökning: "virus neutralization"

Visar resultat 1 - 5 av 42 avhandlingar innehållade orden virus neutralization.

  1. 1. Seroepidemiology of vaccine-preventable and emerging RNA viruses in Rwanda

    Författare :Eric Seruyange; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Seroprevalence; measles virus; rubella virus; Zika virus; West Nile virus; chikungunya virus; tick-borne encephalitis virus; mosquitoes; linear epitopes; Rwanda; Sweden;

    Sammanfattning : Abstract Infectious diseases are a leading cause of death in sub-Saharan Africa, and in Rwanda diarrhea, lower respiratory and other common infections are linked to high mortality and morbidity. For children ... LÄS MER

  2. 2. Virus tropism and neutralization response in SIV infection

    Författare :Anna Laurén; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Naturvetenskap; Natural science; Medicin människa och djur ; Medicine human and vertebrates ; HIV; SIV; mode of CCR5 use; CD4-independence; macrophage tropism; coreceptor use; neutralization; evolution; pathogenesis;

    Sammanfattning : Simian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. LÄS MER

  3. 3. Hepatitis C virus. Aspects on natural history, antibody response, and viral quantification

    Författare :Martin Lagging; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Hepatitis C virus; nosocomial infection; pseudotyped virus; fibrosis; viral quantification;

    Sammanfattning : Hepatitis C virus (HCV) is the major cause of parenterally transmitted non-A, non-B hepatitis, and is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Despite the screening of blood products nosocomial spread of HCV continues to occur. LÄS MER

  4. 4. The role of virus neutralization in primate lentivirus pathogenesis

    Författare :Yi jun Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The antiviral neutralizing activity of sera from primate lentivirus-infected human and monkey hosts was studied. In addition, factors affecting the neutralization reaction were investigated. In simian immunodeficiency virus (SIVsm)-infected macaque monkeys, SIVsm variants able to escape neutralization emerged regularly. LÄS MER

  5. 5. Antibody Evolution and Repertoire Development

    Författare :Johan Lantto; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; virus neutralization; trinucleotide repeat; insertion; immunoglobulin variable genes; human cytomegalovirus; glycoprotein B; deletion; antibody; antibody repertoire;

    Sammanfattning : Antibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. LÄS MER