Sökning: "immune escape"

Visar resultat 1 - 5 av 90 avhandlingar innehållade orden immune escape.

  1. 1. Immune cell infiltration and prognosis in colorectal cancer

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Agnes Ling; Umeå universitet.; [2018]
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Colorectal cancer; molecular subgroups; immune cell infiltration; immune escape; prognosis;

    Sammanfattning : Background: Colorectal cancer (CRC) is globally the second most common form of cancer among women, and third in men. It is also one of the most common causes of cancer-related death in high-income countries. Surgical resection is the basis for curative therapy but still almost half of the patients die from metastatic disease. LÄS MER

  2. 2. Mechanisms of immune escape : Implications for immunotherapy against cancer

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Författare :Karl-Johan Malmberg; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumor Immunology; Immune escape; NK receptors; T lymphocytes; Oxidative stress; Vitamin E;

    Sammanfattning : Tumor cells can be recognized and killed by cytotoxic T cells specific for certain tumor antigens. Immune mediated selection pressure along with genetic instability of tumor cells result in a growth advantage of tumor cells that acquire a less immunogenic phenotype. LÄS MER

  3. 3. Immune modulation in serous epithelial ovarian cancer focus on the role of tumor-derived exosomes

    Detta är en avhandling från Umeå : Umea University

    Författare :Alireza Labani Motlagh; Umeå universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

    Sammanfattning : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. LÄS MER

  4. 4. Human cytomegalovirus immune evasion strategies

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medicine

    Författare :Jenny Odeberg; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Human cytomegalovirus (HCMV) is a member of the herpes virus family. HCMV is a ubiquitous pathogen, causing severe morbidity and mortality in immunocompromised patients, and is a major factor in congenital birth defects. LÄS MER

  5. 5. NK cell recognition of herpesviruses : Mechanisms of viral immune escape

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Microbiology, Tumor and Cell Biology

    Författare :Alexander Rölle; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Herpesviruses are ubiquitous pathogens which after an often asymptomatic infection establish lifelong latency in the host. Control of the viral infection depends on both innate and adaptive immune system. LÄS MER