Sökning: "immune escape"
Visar resultat 16 - 20 av 105 avhandlingar innehållade orden immune escape.
16. Immune modulation in chronic HBV and HCV infection
Sammanfattning : Chronic viral hepatitis is a major health problem worldwide. The two major viral causes for chronic hepatitis are the hepatitis B (HBV) and C viruses (HCV). HBV is a DNA virus with a rather limited genetic variability whereas HCV is an RNA virus with a high genetic variability. LÄS MER
17. Structural insights into glycoprotein transport and viral escape
Sammanfattning : The correct trafficking of proteins through the secretory pathway is essential for the maintenance of cellular functions. Increasing evidence suggests that at least for some glycoproteins, export from the endoplasmic reticulum (ER) is mediated by interaction with cargo receptors. LÄS MER
18. Immunological recognition and tumor escape mechanisms of ovarian carcinoma
Sammanfattning : Ovarian carcinoma is a leading cause of cancer mortality and there is an urgent need for new and better therapeutic modalities that result in improved long-term outcome for this severe malignancy. One promising treatment modality for patients suffering from ovarian carcinoma is immunotherapy. LÄS MER
19. Stress and immune signaling in a Drosophila tumor model
Sammanfattning : Cancer cells contain multiple biological alterations that allow them to escape from host surveillance mechanisms. One of the mechanisms that play an essential role in host protection against tumor growth is immunity. LÄS MER
20. Interactions between Streptococcus pyogenes and the human immune defence
Sammanfattning : Streptococcus pyogenes is an important human pathogen frequently colonizing the throat and skin of humans. To facilitate colonization and spread and to avoid the host immune defence, streptococci are endowed with a variety of virulence factors, two of which are investigated in this thesis namely streptolysin O (SLO) and M protein. LÄS MER