Sökning: "ULBP1-3"

Hittade 2 avhandlingar innehållade ordet ULBP1-3.

1. 1. Mechanisms for immune escape in epithelial ovarian cancer

   Författare :Pernilla Israelsson; Ulrika Ottander; Lucia Mincheva-Nilsson; Eva Lundin; Ivan Nagaev; Karin Sundfeldt; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; ovarian cancer; high-grade serous cancer; EOC; HGSC; HGSOC; tumor microenvironment; immune escape; immune suppression; cytokines; exosomes; NKG2D; MICA B; ULBP1-3; DNAM-1; surgery; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. LÄS MER

3. 2. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes

   Författare :Alireza Labani Motlagh; Lucia Mincheva-Nilsson; Ola Winqvist; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

   Sammanfattning : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. LÄS MER