Sökning: "molecular subgroups"
Visar resultat 1 - 5 av 98 avhandlingar innehållade orden molecular subgroups.
1. Genetic and Epigenetic Profiling of Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia
Sammanfattning : Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) both belong to the group of mature B-cell malignancies. However, MCL is typically clinically aggressive while the clinical course of CLL varies. LÄS MER
2. Molecular Genetic and DNA Methylation Profiling of Chronic Lymphocytic Leukaemia : A Focus on Divergent Prognostic Subgroups and Subsets
Sammanfattning : Advancements in prognostication have improved the subdivision of chronic lymphocytic leukaemia (CLL) into diverse prognostic subgroups. In CLL, IGHV unmutated and IGHV3-21 genes are associated with a poor-prognosis, conversely, IGHV mutated genes with a favourable outcome. LÄS MER
3. Regulatory proteins and the regulation of immune response in Drosophila melanogaster
Sammanfattning : Insect antibacterial peptides are regulated at the transcriptional level. The otherwise silent antibacterial Cecropin genes are strongly induced upon bacterial challenge. LÄS MER
4. Molecular analysis of the oral microbiota of dental diseases
Sammanfattning : Traditionally, bacterial culture has been used for bacterial detection, allowing study of living microorganisms. Molecular methods are rapid and allow simultaneous identification of numerous species and uncultivated phylotypes. LÄS MER
5. Molecular Phylogenetics of Mammals
Sammanfattning : In this thesis, the phylogenetic relationships of the Mammalia have been studied at various levels. Different sources of genetic information have been evaluated and used as phylogenetic markers. These include the well-known mitochondrial genome, cDNA from housekeeping genes and expressed sequence tags from nuclear genes. LÄS MER