Sökning: "human tumours"

Visar resultat 16 - 20 av 181 avhandlingar innehållade orden human tumours.

  1. 16. Characterization of Endocrine Cells and Tumours in the Stomach

    Författare :Apostolos V. Tsolakis; Eva T. Janson; Mats Stridsberg; Guida M. Portela-Gomes; Ola Nilsson; Uppsala universitet; []
    Nyckelord :Oncology; ECL cells; ghrelin cells; gastric endocrine tumours; VMAT-2; ghrelin; obestatin; HDC; U-MeImAA; Onkologi;

    Sammanfattning : Enterochromaffin-like (ECL) and ghrelin cells, in the human gastric mucosa and in gastric endocrine tumours (GETs), were subclassified with respect to immunohistochemical reaction vs. vesicular monoamine transporter 2 (VMAT-2), ghrelin/obestatin, and histidine decarboxylase (HDC). LÄS MER

  2. 17. Angiogenesis in human renal cell carcinoma : hypoxia, vascularity and prognosis

    Författare :Johanna Sandlund; Torgny Rasmuson; Börje Ljungberg; Kjell Grankvist; Anders Bergh; Elisabeth Kjellén; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoglin CD105; CD31; prognosis; CA IX; HIF-2α; renal cell carcinoma; tissue microarray; immunohistochemistry; real-time PCR; stage; grade; Oncology; Onkologi;

    Sammanfattning : Background: Angiogenesis is recognised as a critical step in tumour progression. The angiogenic switch is activated by various trigger signals, such as hypoxia, low pH, and genetic mutations. Renal cell carcinoma (RCC) is often an aggressive tumour, and advanced disease has limited treatment options and bad prognosis. LÄS MER

  3. 18. Prediction of prognosis in human breast cancer : a study on clinicopathologic and cytometric prognostic factors

    Författare :Conny Arnerlöv; Stefan O. Emdin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This study was undertaken to evaluate some important prognostic factors in human breast cancer. The prognostic value of accepted clinicopathological factors such as the presence of axillary lymph node métastasés, histologic grade, clinical and pathological stage was confirmed. LÄS MER

  4. 19. Molecular genetic analysis of human breast cancer

    Författare :Catherine M Phelan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Breast cancer accounts for approximately 20% of all female malignancies with hereditary breast cancer being implicated in 5-10% of these cases. Two highly penetrant hereditary breast cancer genes are known; BRCA1 (17q) and BRCA2 (13q), which also confer an increased risk of cancer at other sites. LÄS MER

  5. 20. Gene and Protein Expression in Human Gliomas

    Författare :Oscar Persson; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumour associated antigen; immunotherapy; glioma; targeted therapy; microarray; proteomics;

    Sammanfattning : The human gliomas are the most common primary brain tumours. They are highly aggressive with a rapid fatal progression for the patient. The invasive growth pattern and inherent resistance to radiation and chemotherapy account for a lack of efficient therapies. LÄS MER