Sökning: "human tumours"

Visar resultat 11 - 15 av 181 avhandlingar innehållade orden human tumours.

  1. 11. ARCON in experimental and clinical radiotherapy

    Författare :Ana Maria Rojas Callejas; Björn Zackrisson; René-Olivier Mirimanoff; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; ARCON; tumours; normal tissues; radiosensitization; carbogen; nicotinamide; repair inhibition; therapeutic gain; rodents; humans; Onkologi; Oncology; Onkologi; onkologi; Oncology;

    Sammanfattning : xHypoxia and repopulation of tumour clonogens are two important determinants of treatment outcome in radiotherapy. In general clinical evidence indicates that loco-regional control may be reduced with long overall treatment times and for tumours with low pre-treatment levels of oxygen. LÄS MER

  3. 12. Methods for selection and optimisation of radiotherapy and early therapy evaluation in breast cancer

    Författare :Tomas Jansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Breast cancer; human; radiotherapy; multi-leaf collimator; breast-conservingsurgery; local recurrence; p53; positron emission tomography; chemotherapy evaluation; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : Adjuvant systemic therapy for breast cancer, the most common malignancy in females, increases survival and this has recently also been demonstrated for postoperative radiotherapy. The aims of this study were to develop an optimised radiotherapeutic technique for postoperative treatment, to analyse the association between p53 status in node-negative patients and radiotherapy, to investigate the incidence of in-breast relapses after conservative surgery and radiotherapy and to determine if positron emissiontomography could be useful for early evaluation of polychemotherapy. LÄS MER

  4. 13. Wnt/β-Catenin Signalling in Parathyroid Tumours

    Författare :Peyman Björklund; Gunnar Westin; Göran Åkerström; Tommy Andersson; Uppsala universitet; []
    Nyckelord :Surgery; Hyperparathyroidism; β-catenin; Mutation; Human parathyroid cell line; LRP5; Alternative splicing; Kirurgi;

    Sammanfattning : Primary hyperparathyroidism (pHPT) due to parathyroid tumours with hypersecretion of parathyroid hormone and hypercalcaemia is a common disease with incompletely understood etiology affecting more than 1 % of the population, primarily postmenopausal women. In secondary hyperparathyroidism (sHPT), parathyroid tumours develop in response to calcium and vitamin D deficiency generally in patients with uraemia. LÄS MER

  5. 14. Oncogenes and tumour suppressor genes in human central nervous system tumours

    Författare :Lu Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human central nervous system (CNS) tumours may arise from both developing and adult brain. Primitive neuroectodermal tumours (PNETs) are the most malignant tumours arising from developing brain, and constitute approximately one third of brain tumours in children. Other common paediatric CNS tumours are ependymomas and pilocytic astrocytomas. LÄS MER

  7. 15. Superoxide dismutase : radiobiological significance : occurrence in human tissues, tumours and tumour cell-lines

    Författare :Gunnar Westman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Superoxide dismutase; Radiation sensitivity; Diethyldithiocarbamate; Haemolysis; Catalase; Glutathione Peroxidase; Potential lethal damage;

    Sammanfattning : .... LÄS MER