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Visar resultat 1 - 5 av 181 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Human cytokeratins : their use as targets in cancer management

   Författare :Birgitta Sundström; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Cytokeratins, biochemically related to intermediate filaments (IF), form an intracellular network of filaments which contributes to the mechanical stabilizing of the cell. 19 individual polypeptides, divided into two groups, constitute the cytokeratin family. LÄS MER

3. 2. Hypoxia and differentiation in human neuroblastoma cells

   Författare :Helén Nilsson; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ontogeny; embryology human ; Utvecklingsbiologi; teratologi; embryologi människa ; teratology; cytogenetik; Development biology; cytogenetics; Genetik; Genetics; Medicin människa och djur ; HIF; Medicine human and vertebrates ; MYCN; Hypoxia; differentiation; Neuroblastoma;

   Sammanfattning : The childhood tumour neuroblastoma is derived from immature cells of the sympathetic nervous system, which have become arrested at different maturation stages. Neuroblastoma is a malignancy with a high degree of heterogeneity, and there is a correlation between a poor differentiation status and a more aggressive phenotype. LÄS MER

4. 3. Studies on the human interferon system : with special reference to patients with carcinoid tumours or recurrent infections

   Författare :Keiko Funa; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

5. 4. Therapeutic dendritic cell vaccination against human papillomavirus

   Författare :Merja Nurkkala Karlsson; Göteborgs universitet; []
   Nyckelord :human papillomavirus; therapeutic dendritic cell vaccination; cholera toxin; T cells; TLRs and CpG;

   Sammanfattning : Cervical cancer, which is caused by infection with human papillomavirus (HPV), is the second most common cancer among women worldwide, leading to 230000 deaths annually. The two currently available HPV vaccines can only be used prophylactically, so they are of no use to the 291 million women who are already infected and at risk of developing cancer. LÄS MER

7. 5. Human Embryonic Stem Cells; A novel model system for early human development

   Författare :Karin Gertow; Lars Ährlund-Richter; Henrik Semb; Karolinska Institute; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human embryonic stem cells; Human embryonic stem cells; model system; differentiation; xeno-grafting; teratoma; development; karyotype; chromosomal integrity; variant.;

   Sammanfattning : Human embryonic stem cells (HESC) have since their first description in 1998 been recognized as a theoretically endless source of cells capable of differentiation into any somatic cell type. Although great attention has been given to their potential use in cell- based therapy, they are equally important as research tools for studies on early human development, both normal and diseased. LÄS MER