Sökning: "human tumours"

Visar resultat 6 - 10 av 181 avhandlingar innehållade orden human tumours.

  1. 6. Human papillomaviruses in skin cancer and cervical cancer

    Författare :Kristin Andersson; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; serology co-factors; non-melanoma skin cancer;

    Sammanfattning : The causal relationship between persistent genital infections with human papillomavirus (HPV) and development of cervical cancer is well established. In contrast, the significance of infections with cutaneous HPV for development of non-melanoma skin cancer (NMSC) is not well understood. LÄS MER

  3. 7. The epidemiology, biology and genetics of human astrocytic tumours

    Författare :Magnus Bäcklund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cancer; cell cycle; apoptosis; astrocytic glioma; glioblastoma; Rb 1 pathway; p53 pathway; EGFR; PTEN; prognosis; parathyroid adenoma; epidemiology;

    Sammanfattning : In Sweden > 1000 primary central nervous system (CNS) tumours are diagnosed each year. The majority are malignant and in adults astrocytic gliomas dominate. LÄS MER

  4. 8. Molecular factors relevant to the radiosensitivity of human tumours

    Författare :Anya Polischouk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :c-Ha-ras; c-myc; radiosensitivity; DNA double-strand break repair; DNA singlestrand repair;

    Sammanfattning : Oncogenes, activated copies of normal cellular genes, are involved in carcinogenesis and have been suggested to be determinants of cellular radiosensitivity (RS). Mutations and gene rearrangement of c-Ha-RAS and c-MYC oncogenes were analysed in 70 biopsies and 51 blood samples from the same patients and compared with RS estimated by the clinical tumour response and by response to irradiation of tumour samples using subrenal capsule assay. LÄS MER

  5. 9. Cancer proteomics : characterisation of protein expression in human epithelial tumours

    Författare :Ayodele A Alaiya; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Two-dimensional gel electrophoresis; protein expression; mass spectrometry; epithelial tumour; heterogeneity;

    Sammanfattning : Defining differences in protein expression between tumour cells of various degrees of malignancy is a first step in the development of markers for tumour diagnosis. In this thesis, the expression of multiple proteins in benign and malignant human ovarian, breast and prostate tumours was examined using two-dimensional gel electrophoresis (2-DE). LÄS MER

  7. 10. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

    Författare :Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

    Sammanfattning : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. LÄS MER