Sökning: "heritability"

Visar resultat 21 - 25 av 154 avhandlingar innehållade ordet heritability.

1. 21. Heredity in Parkinson's disease. From rare mutations to common genetic risk factors

   Författare :Andreas Puschmann; Sektion IV; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; parkinsonism; genetics; alpha-synuclein; SNCA duplicaion; SNCA triplication; LRRK2; PARKIN; PARK2; VPS35; EIF4G1; rare variants; digenic inheritance; heritability;

   Sammanfattning : This study investigated genetic causes of Parkinson's disease (PD) and parkinsonism in southern Sweden. The extensive Lister Family with parkinsonism caused by duplications and triplications of the gene for alpha-synuclein (SNCA) was studied. Clinical, genetic and genealogical data were compiled and evaluated. LÄS MER

3. 22. Life History of the Common Gull (Larus canus) : A Long-Term Individual-Based Study

   Författare :Kalev Rattiste; Mats Björklund; Jon E Brommer; Jan-Åke Nilsson; Uppsala universitet; []
   Nyckelord :Ecology; longitudinal studies; reproductive success; survival; pair bond; indicator trait; breeding time; heritability; selection; Ekologi; Larus canus; ekologisk botanik; Ecological Botany;

   Sammanfattning : An individual’s life history is a sequence of events which eventually determine its contribution to the next generation, or fitness. These events are affected by environmental factors, genetic make-up and decisions made by an individual and its breeding partner. LÄS MER

4. 23. Evolutionary dynamics of migration and breeding in wild birds: genetic architecture, sexual conflicts and evolutionary constraints

   Författare :Maja Tarka; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; quantitative genetics; heritability; intralocus sexual conflict; antagonistic selection; QTL; G-matrix; wing length; arrival date; migration; geolocator; bird; Acrocephalus arundinaceus;

   Sammanfattning : Our knowledge of the evolutionary potential of traits involved in different selective episodes, especially in natural populations, is still limited. This is true for questions such as the genetic basis and inheritance of traits, how natural and sexual selection acts on them, and how selective conflicts influence the evolutionary response to selection. LÄS MER

5. 24. Heritability of blood pressure: monogenes and polygenes

   Författare :Cristiano Fava; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; kidney; Adducin-1; CLC-kb; Gitelman syndrome; association; heritabilty; genetics; hypertension; Blood pressure; blood pressure variability; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. LÄS MER

7. 25. Low back and neck-shoulder pain : work and heritability

   Författare :Teresia Nyman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Low back pain; Neck-shoulder pain; Co-morbidity; Heritability; Twin study; Sickness absence; Occupational exposure; Exposure assessment; Musicians; Performing arts medicine;

   Sammanfattning : Low back pain (LBP) and neck-shoulder pain (NSP) represent a large public health problem being common disorders that often lead to negative consequences for the individual and large costs for Society. The main goal of the thesis is to explore how factors relating to aetiology, i.e. LÄS MER