Sökning: "batch chromatography"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden batch chromatography.

  1. 1. Adsorption Studies with Liquid Chromatography : Experimental Preparations for Thorough Determination of Adsorption Data

    Författare :Lena Edström; Jonas Bergquist; Lars Hagel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid chromatography; HPLC; UHPLC; Reversed phase; Preparative chromatography; Adsorption isotherm; Injection profile; Sample pH; pH stable conditions; Peak deformation; Band distortion; Overloaded band; Chiral preparative chromatography; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : Analytical chemistry is a field with a vast variety of applications. A robust companion in the field is liquid chromatography, the method used in this thesis, which is an established workhorse and a versatile tool in many different disciplines. LÄS MER

  3. 2. Robust Multi-objective Optimization of Rare Earth Element Chromatography

    Författare :Hans-Kristian Knutson; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chromatography; Rare earth elements; Modeling; Multi-objective optimization; Robust optimization; Chromatography; Rare earth elements; Modeling; Multi-objective optimization; Robust optimization;

    Sammanfattning : Rare earth elements comprise the metallic elements known as lanthanides as well as scandium and yttrium. They are extensively used in modern technological industries and are considered as strategic commodities in many countries. LÄS MER

  4. 3. Design of robust preparative chromatography

    Författare :Marcus Degerman; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; sensitivity analysis; optimization; modeling; preparative chromatography; Design space; Control Space; uncertainty analysis;

    Sammanfattning : This work presents a methodology for analyzing and optimizing preparative chromatographic processes. It uses a model-based approach to find the critical process parameters, analyze the control space and suggest a design space that can be registered with the regulatory agencies. LÄS MER

  5. 4. Separation of biomolecules using Open-Loop Non-Isocratic Simulated moving bed (SMB) technology

    Författare :Deepti Sahoo; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Open-loop Non-Isocratic SMB; Simulated moving bed; True moving bed Chromatography; continuous separation; protein purification; batch chromatography;

    Sammanfattning : In biotechnological industries, downstream processing is a bottleneck in the complete production process. There is a wish to reduce the costs and therefore one tries to operate separation technology in continuous mode. LÄS MER

  7. 5. Modeling for Quality and Safety in Biopharmaceutical Production Processes

    Författare :Karin Westerberg; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Process modeling; chromatography; quality by design; robustness; process control;

    Sammanfattning : To design efficient and safe biopharmaceutical production processes, understanding the process and how it is affected by changes in the process conditions is essential. Experimental data form the basis of this understanding which can be enhanced by modeling and simulations of the physical and chemical processes known to control the process. LÄS MER