Sökning: "hepatocyte"

Visar resultat 31 - 35 av 83 avhandlingar innehållade ordet hepatocyte.

  1. 31. Studies of bioactive lipids in cancer

    Författare :Vicky Chatzakos; Petra De Verdier; Jenny Flygare; Åke Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; Sphingolipids; N-acyl amino acids; cancer; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Lipids are a broad class of molecules that, besides being a major form of energy storage and components of cell membranes, act as bioactive signalling molecules. N-acyl taurines are structurally related to endocannabinoids that are known to exert antiproliferative actions in a variety of cancer cells. LÄS MER

  2. 32. On Leukocyte Recruitment in Cholestatic Liver Injury

    Författare :Matthias Laschke; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukocyte and Liver; Inflammation; Cholestasis; Endothelium;

    Sammanfattning : Cholestasis is a frequent clinical syndrome, which is caused by a dysfunction in bile formation of the hepatocyte or from obstruction of the biliary tract. This is associated with inflammation of the liver tissue, resulting in severe liver injury. In this inflammatory process, leukocyte recruitment has emerged as a key feature. LÄS MER

  3. 33. Angiogenesis in childhood malignancies

    Författare :Erik Sköldenberg; Rolf Christofferson; Göran Läckgren; Agneta Nordenskjöld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Angiogenesis Factor; Biopsy; Needle; Neovascularization; Pathologic; Nephroblastoma; Reference value; Kirurgi; Surgery; Kirurgi; Pediatric Surgery; kirurgi; särskilt barnkirurgi;

    Sammanfattning : Angiogenesis is necessary for the growth and spread of solid tumors. In these studies angiogenesis was measured in childhood malignancies in general and in Wilms’ tumor in particular, and cutting needle biopsy (CNB) specimens were evaluated for diagnosis in childhood renal tumors. LÄS MER

  4. 34. Growth factor receptor signalling in thyrocytes of normal and neoplastic origin

    Författare :Daniel Bergström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; thyroid; carcinoma; HGF; Met; TGF-β; EGF; receptor signalling; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Cellular growth and function are controlled by stimulatory and inhibitory factors actingthrough specific receptors. The present thesis focuses on the role of growth factors, theirreceptors and signalling pathways in normal and neoplastic thyroid epithelial cell biology. LÄS MER

  5. 35. Studies on function and regulation of the transcription factor C/EBPalpha

    Författare :Per Flodby; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The transcription factor C/EBPalpha was originally identified as a protein involved in hepatocyte-specific gene regulation. Later, it has been demonstrated that C/EBPalpha is expressed in several other tissues, mainly in adipose cells, lung, intestine, skin and in myeloid cells. LÄS MER