Avancerad sökning

Visar resultat 1 - 5 av 70 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Modern Computational Physical Chemistry : An Introduction to Biomolecular Radiation Damage and Phototoxicity

    Författare :Jorge Llano; Leif A. Eriksson; Ulf Ryde; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; statistical mechanics; biophysical chemistry; interface; surface thermodynamics; bioelectrochemistry; ionizing radiation; radiation therapy; condensed matter; computational chemistry; nucleic acids; radiation damage; electrode potential; electronic transport; photochemistry; strand break; photodynamic action; cytostatic; solvation; solvated electron; absolute potential; chemical potential; Biologi; Biology; Biologi;

    Sammanfattning : The realm of molecular physical chemistry ranges from the structure of matter and the fundamental atomic and molecular interactions to the macroscopic properties and processes arising from the average microscopic behaviour.Herein, the conventional electrodic problem is recast into the simpler molecular problem of finding the electrochemical, real chemical, and chemical potentials of the species involved in redox half-reactions. LÄS MER

  3. 2. Miniaturized localized surface plasmon resonance biosensors

    Författare :Si Chen; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; colloidal lithography; Surface plasmon resonance; biosensing; electron beam lithography; single molecule; hyperspectral imaging; photo functionalization;

    Sammanfattning : Abstract Reliable and sensitive biosensors are required for fast and accurate diagnostics. Localized surface plasmon resonances (LSPRs) in noble-metal nanoparticles possess very high refractive index sensitivity close to the metal surface and therefore constitute an attractive biosensing platform. LÄS MER

  4. 3. α-Synuclein Fibril Formation and the Effects of Lipid Membranes

    Författare :Ricardo Gaspar; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein misfolding; alpha-synuclein; Parkinson s disease; microscopic rate constants; Thioflavin T; ganglioside lipids; Exosomes; protein-lipid co-aggregation; model membranes; monomer-dependent secondary nucleation;

    Sammanfattning : Amyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. LÄS MER

  5. 4. Biomarkers aiming at cancer risk estimation of polycyclic aromatic hydrocarbons

    Författare :Hans Helleberg; Kimmo Peltonen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

    Sammanfattning : Polycyclic aromatic hydrocarbons (PAH), a family of compounds that are formed in incomplete combustion of organic matter, occur as general pollutants in air and food. Exposure to PAH is, according to preliminary estimates, associated with non-acceptable cancer risks showing the need for improved data to be used in risk estimation. LÄS MER

  7. 5. Microbial biofilm communities associated with degradation of sprayed concrete in subsea tunnels

    Författare :Sabina Karacic; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; marine environment; subsea tunnels; surface structure; biofilm; steel fibers; metagenomics.; microbially induced deterioration; amplicon sequencing; concrete;

    Sammanfattning : Deterioration of concrete leads to reduced structural strength implying high societal challenge with huge economic impact. In the Oslofjord subsea tunnel, complex microbial biofilm activity together with abiotic attack from saline groundwater are responsible for concrete matrix degradation and steel fiber corrosion. LÄS MER