Sökning: "strand break"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden strand break.

  1. 1. Hjälp mig att hjälpa dig! : upplevelser och uppfattningar av undersökning med MRT för personer med metastaser i ryggen

    Författare :Thomas Strand; Åsa Roxberg; Erna Törnqvist; Mikael Rask; Solveig Lundgren; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; spinal metastasis; patient-centered care; Vårdvetenskap; Caring Science;

    Sammanfattning : Aim: The overall aim was to explore how patients with spinal metastasesexperience a magnetic resonance imaging examination (MRI). Furthermore,the purpose was to investigate the radiographers’ perceptions of the patients’care needs and what measures can be taken to relieve the suffering associatedwith an MRI examination. LÄS MER

  3. 2. Känsliga bitar : text- och kontextstudier i sentimental populärsång

    Författare :Karin Strand; Umeå universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Literature; cultural studies; gender studies; kitsch; lyrics; nostalgia; popular culture; popular music; schlager; sentimentality; Litteraturvetenskap; Literature; Litteraturvetenskap; Literature; litteraturvetenskap;

    Sammanfattning : The dissertation is a study of a song type that was popular during the whole of the twentieth century: the sentimental schlager. As a sub-genre of the dance and high-spirited mainstream schlager these songs are characterized by nostalgia and sentimentality. LÄS MER

  4. 3. DNA double-strand break repair in ascomycetes

    Författare :Jiang Chen; Stefan Åström; Michael Lisby; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : Nonhomologous end joining (NHEJ) and homologous recombination (HR) are two pathways for DNA double strand break (DSB) repair. We found that the NHEJ protein Nej1 interacted physically with the HR protein Srs2, which was dependent on phosphorylation of Nej1 by Dun1. Srs2 recruitment to a DSB partly relied on Nej1 and Dun1. LÄS MER

  5. 4. Measurements of the DNA double-strand break response

    Författare :Aida Muslimovic; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DSB response; cancer patients; H2AX phosphorylation;

    Sammanfattning : Radiotherapy and some chemotherapeutic drugs kill cancer cells by induction of the extremely toxic DNA double-strand breaks (DSBs). Measurements of the DSB response in patients during therapy could allow personalized dosing to improve tumor response and minimize side effects. LÄS MER

  7. 5. Recognition and signaling of DNA double-strand breaks in human cells

    Författare :Ismail Hassan Ismail; Göteborgs universitet; []
    Nyckelord :DNA-PK; DNA double-strand break; DSB; DNA single-strand break; SSB; DNA damage; ionizing radiation; IR; DNA repair; calicheamicin kappa1; ATM; hydrogen peroxide; H2AX; radiotherapy; radiosensitizer; flow cytometry;

    Sammanfattning : DNA double-strand breaks (DSBs) are the most toxic type of DNA damage. Fortunately, our cells have highly conserved pathways that detect and repair DSBs. Defects in DSB signaling and DSB repair pathways result in genomic instability that predisposes for cancer development. LÄS MER