Sökning: "photodynamic action"

Hittade 4 avhandlingar innehållade orden photodynamic action.

  1. 1. Modern Computational Physical Chemistry : An Introduction to Biomolecular Radiation Damage and Phototoxicity

    Författare :Jorge Llano; Leif A. Eriksson; Ulf Ryde; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; statistical mechanics; biophysical chemistry; interface; surface thermodynamics; bioelectrochemistry; ionizing radiation; radiation therapy; condensed matter; computational chemistry; nucleic acids; radiation damage; electrode potential; electronic transport; photochemistry; strand break; photodynamic action; cytostatic; solvation; solvated electron; absolute potential; chemical potential; Biologi; Biology; Biologi;

    Sammanfattning : The realm of molecular physical chemistry ranges from the structure of matter and the fundamental atomic and molecular interactions to the macroscopic properties and processes arising from the average microscopic behaviour.Herein, the conventional electrodic problem is recast into the simpler molecular problem of finding the electrochemical, real chemical, and chemical potentials of the species involved in redox half-reactions. LÄS MER

  3. 2. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery

    Författare :Vladimir Kirejev; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photodynamic therapy; PDT enhancement; Nitric oxide; NO-based PDT; Targeted drug delivery; Galectin-3; mTHPP; Cyclodextrin; CD-mTHPP conjugate; PpIX AuNP combination; Two-photon microscopy; FLIM; Cell phototoxicity; Ex vivo skin;

    Sammanfattning : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. LÄS MER

  4. 3. Photdynamic therapy for treatment of Acne Vulgaris in clinical studies; dose response and mode of action

    Författare :Camilla Hörfelt; Göteborgs universitet; []
    Nyckelord :Photodynamic therapy; Acne Vulgaris; Delta-aminolaevulinic acid; Methyl-aminolaevulinic acid; Porphyrins; Propionibacterium acnes; Fluorescence imaging;

    Sammanfattning : This thesis deals with the use of photodynamic therapy (PDT) for treatment of Acne Vulgaris. Acne Vulgaris is one of the most common skin disorders. Conventional treatments target the pathogenic factors and include a variety of topical and oral medications such as antibiotics. LÄS MER

  5. 4. DNA-Photosensitization by New Drugs for Photoinactivation of Viruses and Phototherapy of Tumors

    Författare :Claire Kanony; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 7; hydroxyl radicals; singlet oxygen; 8-dihydro-8-oxo-deoxyguanosine; pyropheophorbides; electron transfer; DNA damage; hydrogen abstraction; cyanine dyes;

    Sammanfattning : Cyanines and pyropheophorbides are two classes of photoactivable dyes which are particularly interesting for photosterilization of blood used in transfusion and for treatment of localised cancers by photodynamic therapy (PDT). After a bibliographic review about the principal mechanisms of DNA photosensitization, studies about the photosensitizing properties of these two families of compounds are presented. LÄS MER