Sökning: "forkhead"

Visar resultat 6 - 10 av 36 avhandlingar innehållade ordet forkhead.

  1. 6. FOXC2 : a regulator of adipocyte metabolism

    Författare :Anna Cederberg; Göteborgs universitet; []
    Nyckelord :FOXC2; forkhead; winged helix; obesity; diabetes; adipocyte; insulin resistance;

    Sammanfattning : Obesity, hyperlipidemia and insulin resistance are common forerunners of type 2 diabetes, a serious and increasingly prevalent disease in both the industrialised part of the world as well as in third world countries. We have identified the human transcription factor gene FOXC2 as a key regulator of adipocyte metabolism. LÄS MER

  3. 7. Cloning and characterization of human forkhead proteins

    Författare :Stefan Pierrou; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 8. Foxf2 and Foxc2, two transcription factors that regulate adipocyte metabolism

    Författare :Rickard Westergren; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; forkhead genes; insulin signaling; glucose metabolism; adipose tissue; angiogenesis; Foxc2; Foxf2; Irs1; insulin resistance; Ang-2;

    Sammanfattning : Type 2 diabetes is the most common metabolic disorder today and has reached epidemic proportions in many countries. Diet-induced insulin resistance plays a central role in the development of type 2 diabetes. LÄS MER

  5. 9. FoxF genes in development and disease

    Författare :Seyed Ali Moussavi Nik; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FOXF1; Sfrp1; LGR5 stem cells; Tgfb; Wnt signaling; ECM; Intact intestinal epithelium; Foxf2; ACDMPV;

    Sammanfattning : Forkhead transcription factors of the FoxF group are important during embryonic de-velopment, and mutation of either of the members, Foxf1 and Foxf2, has fatal conse-quences. In this thesis, I present our recent findings about the mechanism of action of FoxF genes in development and disease. LÄS MER

  7. 10. FOXC2 and CAPN10 as candidate genes for obesity, insulin resistance and type 2 diabetes

    Författare :Emma A Nilsson; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; Type 2 diabetes; Genetics; Obesity;

    Sammanfattning : The worldwide prevalence of obesity and type 2 diabetes is increasing rapidly. Both disorders depend on genetic and environmental factors. The studies included in this thesis investigated the possible association of the FOXC2 and CAPN10 genes with obesity, insulin resistance, type 2 diabetes, and related phenotypes. LÄS MER