Sökning: "forkhead"

Visar resultat 1 - 5 av 29 avhandlingar innehållade ordet forkhead.

  1. 1. Forkhead Genes in Mammalian Development

    Författare :Henrik Landgren; Göteborgs universitet.; Gothenburg University.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Development; Forkhead;

    Sammanfattning : This thesis concerns aspects of Forkhead gene biology and it’s relation to mammalian development. Genes from three subclasses are discussed, Foxj3, Foxf1 and f2, and Foxe3. LÄS MER

  2. 2. Functional studies of two forkhead genes

    Författare :Mikael Heglind; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; forkhead genes; Foxs1; Foxi1; vacuolar type H -ATPase; boundary cap; neural crest stem cells;

    Sammanfattning : Forkhead genes are functionally diverse and several have been linked to human disease. A previous screen for forkhead genes identified the family member FOXS1. To characterize the function of this gene, we produced a mouse model in which the Foxs1 gene was replaced by a lacZ marker allele. LÄS MER

  3. 3. Mechanisms of survival and maintenance of Hematopoietic Stem Cells and Multipotent Progenitor Cells

    Detta är en avhandling från Richard Karlsson Entr. 78, 3rd floor, U-MAS, S-205 02 Malmö, Sweden

    Författare :Richard Karlsson; Lund University.; Lunds universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellulära vätskor; Hematologi; extracellular fluids; Haematology; hypoxia.; forkhead; Akt PKB; Bcl-2; apoptosis; Flt3; FL; c-kit; KL; cytokines; Hematopoiesis; progenitor;

    Sammanfattning : Hematopoietic stem cells and progenitor cells are maintained in the bone marrow microenvironment, where factors including soluble and membrane-bound cytokines influence the processes of self-renewal, proliferation and differentiation. Two nonreduntant cytokines with effects on hematopoiesis, Kit Ligand (KL) and Flt3 Ligand (FL), signal via related tyrosine kinase receptors, c-kit and Flt3. LÄS MER

  4. 4. Regulation of Mast Cell Survival

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christine Möller; Uppsala universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; mast cell; A1; Bfl-1; Bim; Bcl-2 family members; basophil; SCF; forkhead; survival; Patologi; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi;

    Sammanfattning : Mast cells are long-lived effector cells of importance for both acute and chronic inflammations. Mast cells can be activated in many different ways, leading to the release of inflammatory mediators. In contrast to most other inflammatory cells, activated mast cells have the capacity to recover, regranulate and thereby be activated again. LÄS MER

  5. 5. FOXC2 : a regulator of adipocyte metabolism

    Detta är en avhandling från Göteborg

    Författare :Anna Cederberg; Göteborgs universitet.; Gothenburg University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FOXC2; forkhead; winged helix; obesity; diabetes; adipocyte; insulin resistance;

    Sammanfattning : Obesity, hyperlipidemia and insulin resistance are common forerunners of type 2 diabetes, a serious and increasingly prevalent disease in both the industrialised part of the world as well as in third world countries. We have identified the human transcription factor gene FOXC2 as a key regulator of adipocyte metabolism. LÄS MER