Sökning: "Foxc2"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet Foxc2.
1. FOXC2 : a regulator of adipocyte metabolism
Sammanfattning : Obesity, hyperlipidemia and insulin resistance are common forerunners of type 2 diabetes, a serious and increasingly prevalent disease in both the industrialised part of the world as well as in third world countries. We have identified the human transcription factor gene FOXC2 as a key regulator of adipocyte metabolism. LÄS MER
2. Foxf2 and Foxc2, two transcription factors that regulate adipocyte metabolism
Sammanfattning : Type 2 diabetes is the most common metabolic disorder today and has reached epidemic proportions in many countries. Diet-induced insulin resistance plays a central role in the development of type 2 diabetes. LÄS MER
3. FOXC2 and CAPN10 as candidate genes for obesity, insulin resistance and type 2 diabetes
Sammanfattning : The worldwide prevalence of obesity and type 2 diabetes is increasing rapidly. Both disorders depend on genetic and environmental factors. The studies included in this thesis investigated the possible association of the FOXC2 and CAPN10 genes with obesity, insulin resistance, type 2 diabetes, and related phenotypes. LÄS MER
4. Human iris characteristics as biomarkers for personality
Sammanfattning : This dissertation explains why behavioral genetic research can be better informed by using characteristics in the human iris as biomarkers for personality, and is divided into five parts. Part I gives an introduction to the classical twin method and an overview of the findings that have led most developmental researchers to recognize that the normal variation of personality depends on a complex interplay between genetic and environmental factors. LÄS MER
5. Mechanism of pathological angiogenesis in adipose tissue and tumor
Sammanfattning : Angiogenesis is critical for both malignant diseases, such as cancer, and non-malignant diseases, such as obesity and metabolic disorders. Majority of tissues and organs are highly vascularized. The malfunctions of tissue microenvironment are always accompanied with or dependent on the alterations of vasculature. LÄS MER