Sökning: "Bcl-2 family members"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden Bcl-2 family members.
1. Studies on the Bcl-2 Family of Apoptosis Regulators in the Nervous System
Sammanfattning : Apoptosis is a type of cell death with a specific morphology and molecular program, which is essential for the development of the nervous system. However, inappropriate cell death has been implicated in several neurodegenerative diseases. LÄS MER
2. The impact of Bcl-2 family members on mast cell survival and apoptosis
Sammanfattning : Mast cells are long-lived effector cells of the immune system perhaps best known for their involvement in allergic diseases. There are several acute and chronic inflammations where mast cell accumulation, activation and release of mediators are important for the initiation and perpetuation of the inflammation. LÄS MER
3. Aspects of pathological apoptosis in the immature brain after hypoxia-ischemia
Sammanfattning : The cause of mechanisms underlying perinatal brain injury is not fully known, but it results in a wide variety of neurological impairments in the affected children. When injured, neurons of the newborn brain are prone to undergo programmed cell death, apoptosis, since this genetic program is normally activated in some cells during development of the nervous system, even in the perinatal period. LÄS MER
4. Regulation of Apoptosis in Hematopoietic Progenitor Cells: Involvement of Different Signaling Pathways
Sammanfattning : Proliferation, differentiation, and survival of hematopoietic stem cells and multipotent progenitor cells are regulated by cytokines and cell-cell interactions. Kit ligand (KL) and Flt3 ligand (FL) have pleiotropic effects, promotes survival, but are nonredundant. LÄS MER
5. Apoptosis And Excitotoxicity In The Death of Cultured And Grafted Dopaminergic Neurones
Sammanfattning : Over the past two decades, grafting of embryonic nigral tissue has developed into a feasible therapeutic strategy for Parkinson's disease (PD). It has become apparent that the degree of restoration of dopaminergic neurotransmission by the transplanted cells is highly correlated to the symptomatic relief. LÄS MER