Sökning: "mucus"

Visar resultat 1 - 5 av 101 avhandlingar innehållade ordet mucus.

  1. 1. Colonic mucus structure and processing

    Författare :Elisabeth E. L. Nyström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucus; CLCA1; Goblet cell; Spdef;

    Sammanfattning : The mucus layer covering the colonic epithelium creates a crucial first line of defense against the gut residing bacteria. Several lines of evidence suggest that a functional mucus layer is essential for health. For example, it is. suggested that ulcerative colitis is correlated with mucus layer defects. LÄS MER

  2. 2. The MUC2 mucin -A network in the intestinal protective mucus

    Författare :Malin E V Johansson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :mucus; Muc2; trimer; proteomics; intestine; colitis; DSS;

    Sammanfattning : The intestine is covered by mucus that is the first line of defence of the epithelium. The main structural component of the intestinal mucus is the MUC2 mucin. This is a large glycoprotein with two long and heavily O-glycosylated mucin domains. LÄS MER

  3. 3. Mucus associated proteins and their functional role in the distal intestine

    Författare :Joakim H. Bergström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucus; bacteria; MUC2; AGR2; FCGBP; ZG16;

    Sammanfattning : The mammalian intestine, especially the large intestine, harbors complex societies of beneficial bacteria coexisting with the host. This is a mutualistic relationship, where the host provides nutrients and a favorable environment while the bacteria in return ferment indigestible polysaccharides to short chain fatty acids. LÄS MER

  4. 4. Colonic barrier function in ulcerative colitis - Interactions between ion and mucus secretion

    Författare :Jenny K Gustafsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :intestine; mucus; ion transport; colitis; CFTR;

    Sammanfattning : Anion and mucus secretions have traditionally been looked upon as two separate parts of the epithelial defense system. The importance of anion secretion has been attributed to its role in creating the driving force for fluid secretion that flushes the epithelium from bacteria, while mucus secretion ensures protection via the mucus layer that forms a physical barrier between the bacteria and the epithelium. LÄS MER

  5. 5. Citrobacter rodentium and Escherichia coli interactions with mucus producing colonic epithelical cells

    Författare :Sinan Sharba; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; A E pathogens; cytokines; epithelium; mitochondria; mucus;

    Sammanfattning : The epithelial cells together with the mucus layer protect the host from noxious luminal substances and pathogenic invasion. Pathogens have evolved numerous strategies to circumvent these barriers and mount infection. C. rodentium is a murine model for the attaching and effacing intestinal E. LÄS MER