Sökning: "exosomal"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet exosomal.

  1. 1. Exosomal Shuttle RNA

    Författare :Karin Ekström; Göteborgs universitet; []
    Nyckelord :exosomes; exosomal; shuttle; RNA; esRNA; vesicles; mast cell; gene transfer; microRNA;

    Sammanfattning : Exosomes are small membrane nanovesicles of endocytic origin that can be released by many different cells to the extracellular environment. Exosomes have been found in a number of body fluids such as blood plasma, breast milk, bronchoalveolar lavage fluid and urine, indicating relevance in vivo. LÄS MER

  3. 2. Analytical Approaches to Study Vesicular and Exosomal Release

    Författare :Kim Long Le Vo; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Vesicles, as a special type of entity nanometers in size, are crucial for survival of multicellular organisms. Intracellular vesicles mainly contain specific signaling molecules, transmitters, and modulators whereas extracellular vesicles (EVs) are bioactive organelles carrying a wide range of proteins, genetic materials, and other molecules. LÄS MER

  4. 3. Advances in exosome-mediated immunotherapy and diagnostics

    Författare :Pia Larssen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Exosomes are small vesicles with immune-stimulatory capacity, which can activate T cell responses in a B cell dependent manner, and therefore may serve as immune therapeutic tools. Peptide-loaded dendritic cell (DC)-derived exosomes are proven safe in clinical trials, although with limited ability to induce cytotoxic T lymphocyte (CTL) responses or prolong patient survival. LÄS MER

  5. 4. Physical characterization of exosomes and other extracellular vesicles using surface-based sensing

    Författare :Deborah Rupert; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nanoparticle tracking analysis; exosomes; scattering; surface-based biosensing; optical density; cluster of differentiation 63 CD63 ; liposomes; label-free; fluorescence; surface plasmon resonance; Extracellular vesicles; specificity; antibody; lipid content; single particle; quantification; size distribution; optical waveguide microscopy;

    Sammanfattning : Extracellular vesicles (EVs) are hundred of nanometer sized particles secreted by almost all cell types. Exosomes are one type of EVs today intensively investigated due to the increased evidence suggesting that they play important roles as communicating vehicles in a broad range of physiological processes, pathological conditions and disease diagnostics. LÄS MER

  7. 5. Regenerative effects of mesenchymal stem cell-derived exosomes

    Författare :Xiaoqin Wang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aging; cell adhesion; cell-material interaction; exosomes; extracellular vesicles; mesenchymal stem cells; osteogenic differentiation; proliferation; regeneration; titanium;

    Sammanfattning : Mesenchymal stem cells (MSCs) play pivotal roles for bone regeneration by virtue of their osteogenic differentiation ability and immunomodulatory capacity. Recently, secretion of exosomes/extracellular vesicles (EVs) has been suggested as a new mechanism of MSC-based therapy. LÄS MER