Sökning: "electrospray ionization"

Visar resultat 36 - 40 av 84 avhandlingar innehållade orden electrospray ionization.

  1. 36. Development and application of alternative methods for profiling proteins N-glycosylation

    Författare :Alessandro Quaranta; Leopold Ilag; Niclas Karlsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; N-glycosylation; Glycomics; Glycosylation Biomarkers; Intact Glycoproteins; Glycoform Quantification; Mass Spectrometry; Ion Mobility Spectrometry; MALDI-MS; Paper Spray Ionization; Microfluidics; Magnetic Beads; Immunoaffinity Purification; Nanobodies; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Glycosylation is a post-translational modification (PTM) that exerts profound structural and functional effects on the modified protein. Glycan synthesis and conjugation to proteins are regulated by a myriad of factors, both genetic and environmental, and are also influenced by external stressors. LÄS MER

  3. 37. Capillary zone electrophoresis for the analysis of low molecular weight organic acids in environmental systems

    Författare :Jessika Hagberg; Bert Allard; Stefan Karlsson; Anders Düker; Patrick van Hees; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; capillary zone electrophoresis; capillary zone electrophoresis-electrospray ionization-mass spectrometry; low molecular weight organic acids; pKa; Chemistry; Kemi; Kemi; Chemistry;

    Sammanfattning : Capillary zone electrophoretic (CZE) methods were developed to identify and quantify low molecular weight (LMW) organic acids in environmental samples. Sensitivity and selectivity were optimised by adapting the background electrolyte to the characteristics of analytes, and by using different modes of detection and injection. LÄS MER

  4. 38. LDI-MS strategies for analysis of polymer degradation products, additives and drugs

    Författare :Nina Aminlashgari; Minna Hakkarainen; Peter J. Schoenmakers; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; laser desorption ionization-mass spectrometry LDI-MS ; surface; polymer degradation products; additive; drugs; nanoparticles; nanocomposites; Kemi; Chemistry;

    Sammanfattning : The advancement of mass spectrometry (MS) has been and continues to be a prominent analytical technique for highly accurate determination of analytes. The goal of this thesis was to develop new laser desorption ionization-mass spectrometric (LDI-MS) methods for analysis of polymer degradation products, additives and drugs. LÄS MER

  5. 39. Structural studies towards the understanding of biosynthesis of the lipopolysaccharide of Haemophilus influenzae

    Författare :Anna Risberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Haemophilus influenzae; structural investigation; lipopolysaccharide LPS ; NMR and electrospray ionization mass spectrometry ESI-MS ;

    Sammanfattning : The thesis Structural studies towards the understanding of biosynthesis of the lipopolysaccharide of Haemophilus influenzae involves structural investigation of LPS of four different H. influenzae strains, RM.118-28, RM.118, RM118-26 and RM. LÄS MER

  7. 40. SALDI-MS Method Development for Analysis of Pharmaceuticals and Polymer Degradation Products

    Författare :Nina Aminlashgari; Minna Hakkarainen; Klas Engvall; Åsa Emmer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Surface assisted laser desorption ionization-mass spectrometry SALDI-MS ; polyester degradation products; pharmaceutical compounds; nanoparticles; nanocomposites.;

    Sammanfattning : Surface assisted laser desorption ionization-mass spectrometry (SALDI-MS) was evaluated as a new tool for analysis of polymer degradation products. A SALDI method was developed enabling rapid analysis of low molecular mass polyesters and their degradation products. LÄS MER