Sökning: "early clinical studies"

Visar resultat 16 - 20 av 1413 avhandlingar innehållade orden early clinical studies.

  1. 16. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals

    Författare :Midori Kjellin; Johan Lennerstrand; Nina Weis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; HCV; DAA; RAS; resistance-associated substitution; baseline resistance; NS5A; NS3; SVR; Medical Virology; Medicinsk virologi; Mikrobiologi; Microbiology; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. LÄS MER

  3. 17. Adoption studies on psychiatric illness : epidemiological, environmental and genetic aspects

    Författare :Anne-Liis von Knorring; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adoption; adoption outcome; psychiatric illness; gene-environment; early experience; somatoform disorders; affective disorders; substance abuse; sick-leave;

    Sammanfattning : The aim of this study is to evaluate the outcome of adoptions and to study the gene-environment influences on psychiatric illness as well as sick-leave patterns. The material consists of 2 966 adopted persons born between 1917 and 1949, their 5 932 adoptive parents and 5 438 identified biological parents. LÄS MER

  4. 18. Lung Transplantation: Clinical and experimental studies

    Författare :Leif Eriksson; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Respiratory system; Follow up Studies; Vascular Resistance; Intensive Care; Induced; Hypothermia; Swine; Extracorporeal Circulation; Lung Transplantation; Organ Preservation; Andningsorganen; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : During the past 15 years lung transplantation has been established as a therapeutic option for patients with end-stage pulmonary disease. The results have improved over time and some transplantation centers now show 1-year survival rates above 80%. LÄS MER

  5. 19. Optimization of the perioperative anaesthetic care for prostate cancer surgery : clinical studies on pain, stress response and immunomodulation

    Författare :Federica Fant; Anil Gupta; Kjell Axelsson; Swen-Olof Andersson; Sigridur Kalman; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radical retropubic prostatectomy; epidural analgesia; patientcontrolled local anaesthesia; patient-controlled analgesia; surgical stress response; local and general inflammatory reaction; immune response; Anaesthesiology; Anestesiologi; Surgery; Kirurgi;

    Sammanfattning : Prostate cancer (PC) is the most common cancer form in men. Surgery is the treatment of choice for localized form of PC and half of all surgical procedures are radical retropubic prostatectomies (RRP). LÄS MER

  7. 20. Clinical-epidemiological studies on cutaneous malignant melanoma : A register approach

    Författare :Johan Lyth; John Carstensen; Christer Lindholm; Hans Starkhammar; Håkan Olsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; early detection; population-based; registers; time trends; survival; prognostic factors; tumour thickness; stage at diagnosis; level of education; socioeconomic status; healthcare costs;

    Sammanfattning : The incidence of cutaneous malignant melanoma (CMM) is steadily increasing. Most of the patients have thin CMM with a good prognosis and a 5-year survival of about 90%. The prognosis is highly related to tumour thickness and clinical stage at diagnosis. LÄS MER