Sökning: "Swine"
Visar resultat 1 - 5 av 54 avhandlingar innehållade ordet Swine.
1. On intestinal ischaemia after aortoiliac surgery : Epidemiological, clinical and experimental studies
Sammanfattning : An important cause of death among patients undergoing surgery of the abdominal aorta is intestinal ischaemia. In the Swedish Vascular Registry 2930 aortoiliac operations were identified. The complication was studied in a combined cohort and case-control study, and multivariate analysis performed. The incidence of intestinal ischaemia was 2. LÄS MER
2. Intestinal effects of lung recruitment maneuvers
Sammanfattning : Background and aims: Lung recruitment maneuvers (brief episodes of high airway pressure) are a modern treatment alternative to achieve open lung conditions under mechanical ventilation of patients with acute lung injury. It is well known that positive pressure ventilation with high airway pressures cause negative circulatory effects, and that the effects on regional vascular beds can be even more pronounced than the systemic effects. LÄS MER
3. Lung Transplantation: Clinical and experimental studies
Sammanfattning : During the past 15 years lung transplantation has been established as a therapeutic option for patients with end-stage pulmonary disease. The results have improved over time and some transplantation centers now show 1-year survival rates above 80%. LÄS MER
4. Olfactory Transfer of Analgesic Drugs After Nasal Administration
Sammanfattning : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. LÄS MER
5. Models for the Transfer of Drugs from the Nasal Cavity to the Central Nervous System
Sammanfattning : The blood-brain barrier restricts the access of many compounds, including therapeutic agents, to the brain. Several human studies indicate that nasal administration of hydrophilic compounds, such as peptides, can bypass the blood-brain barrier. The aims of this thesis were to develop and refine models for this direct nose-to-brain transfer. LÄS MER