Sökning: "drug susceptibility testing"
Visar resultat 1 - 5 av 25 avhandlingar innehållade orden drug susceptibility testing.
1. Tuberculosis : diagnosis and drug susceptibility testing where resources are scarce
Sammanfattning : Background: Tuberculosis remains a major global public health problem. Not surprisingly, most cases of this disease occur in poor countries and an increasing number of patients harbor drug - resistant bacteria. The cornerstone of bacteriological diagnosis of tuberculosis is direct sputum smear microscopy. LÄS MER
2. Species specific susceptibility testing for ß-lactam antibiotics. With special reference to staphylococci
Sammanfattning : The main objective of this thesis was to identify methods for the detection of ß-lactam resistance in staphylococci, bacteria often causing nosocomial infections. Detection of ß-lactam resistance in these species is difficult due to strong regulation of genes encoding for the two main resistance mechanisms, ß-lactamase production and the penicillin-binding protein (PBP) 2?. LÄS MER
3. Water-swelling tablets based on hydrophobically modified poly(acrylic acid) - Effects of amphiphiles on swelling and drug release
Sammanfattning : An important issue within the pharmaceutical world today is the increasing number of poorly soluble drugs. These often show a low bioavailability and a susceptibility to varying conditions in the intestine. LÄS MER
4. Drug-resistant Mycobacterium tuberculosis in Estonia
Sammanfattning : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. LÄS MER
5. Rapid assessment of drug susceptibility and mutation to resistance in mycobacterium tuberculosis Beijing type
Sammanfattning : The increasing rates of multidrug resistant tuberculosis (MDR-TB) worldwide, are seriously threatening the TB control efforts. The present thesis was aimed at increasing the knowledge about the role of different factors, such as the development of drug resistance and the efficacy of drug susceptibility assessments, in the problem with MDR-TB. LÄS MER