Sökning: "rrs mutations"

Hittade 3 avhandlingar innehållade orden rrs mutations.

1. 1. Drug-resistant Mycobacterium tuberculosis in Estonia

   Författare :Annika Krüüner; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Tuberculosis; Estonia; M. tuberculosis; drug resistance; MDR-TB; Beijing genotype; cross-resistance; kanamycin; amikacin; rrs mutations; 16S rRNA; exposure; nosocomial transmission; mycobacterial persistence; re-infection; DST; second-line drugs; Bactec; 460; DNA fingerprinting; spoligotyping;

   Sammanfattning : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. LÄS MER

3. 2. Molecular characterisation of antibiotic resistance in Mycobacterium tuberculosis

   Författare :Pontus Juréen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : To counteract the emergence of multi-drug resistant tuberculosis (MDR-TB) a number of approaches have been proposed, amongst which are the sound usage of the present anti-TB drugs and the development of prompt and specific tools for the diagnosis of resistance. To examine the role of drugs in the treatment of resistant TB, we investigated the general crossresistance between kanamycin and amikacin, which has been reported in numerous studies. LÄS MER

4. 3. Molecular detection and characterization of drug-resistant Mycobacterium tuberculosis

   Författare :Anna Engström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Tuberculosis (TB) is an ancient disease, but not a disease of the past. Despite the declaration of TB as a global emergency by the World Health Organization in 1993 the worldwide problem of TB has worsened. LÄS MER