Sökning: "mycobacterial persistence"
Hittade 3 avhandlingar innehållade orden mycobacterial persistence.
1. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes
Sammanfattning : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. LÄS MER
2. Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance
Sammanfattning : IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages in vitro. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. LÄS MER
3. Drug-resistant Mycobacterium tuberculosis in Estonia
Sammanfattning : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. LÄS MER