Sökning: "cyclophosphamide"

Visar resultat 21 - 25 av 54 avhandlingar innehållade ordet cyclophosphamide.

  1. 21. Vaccination in gastrointestinal cancer

    Författare :Caroline Staff; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CEA;

    Sammanfattning : Advances in immunology have increased the possibility to develop therapeutic cancer vaccines (TCV), as a complementary approach to standard treatment. The goal of a successful cancer vaccine is to induce a potent long-lasting immune response against the tumour with limited toxicity on normal cells. LÄS MER

  3. 22. B cell depleting therapy in systemic lupus erythematosus

    Författare :Thórunn Jónsdóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Systemic Lupus Erythematosus; Lupus nephritis; B cells; rituximab;

    Sammanfattning : Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease characterized by multiple organ involvement, production of a wide range of autoantibodies and local formation or tissue deposition of immune complexes in the affected organs. Lupus nephritis (LN) is a common and serious organ involvement in patients with SLE. LÄS MER

  4. 23. Experimental treatment of patients with disseminated malignant melanoma

    Författare :Aglaia Schiza; Gustav Ullenhag; Angelica Loskog; Sara Mangsbo; Thomas Tötterman; Ola Winqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malignant melanoma; AdCD40L; immunotherapy; proteomics; DW-MRI; FDG-PET CT; prediction; early response; BRAF-inhibitor; vemurafenib; Oncology; Onkologi;

    Sammanfattning : Malignant melanoma (MM) is the deadliest skin cancer with an ever-increasing incidence. New treatments have improved the prognosis for patients with advanced MM. Still, most patients do not respond, and the side effects can be severe, underlining the need for better therapies. LÄS MER

  5. 24. Biological markers and treatment as prognostic factors in multiple myeloma

    Författare :Katarina Uttervall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple myeloma (MM) is an incurable disease with an increasing number of treatment options. The introduction of what are called novel drugs (bortezomib, lenalidomide and thalidomide) was an important step. LÄS MER

  7. 25. Skin fibrosis, internal organ involvement and auto antibodies in systemic sclerosis: longitudinal development and impact on survival

    Författare :Roger Hesselstrand; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; proteoglycan; pulmonary hypertension; organ involvement; auto antibodies; survival; systemic sclerosis; prognosis;

    Sammanfattning : Systemic sclerosis (SSc) is a connective tissue disease with a highly variable prognosis. Since new treatment strategies are emerging, there is a need for prognostic markers in order to help allocate patients to the optimal treatment. LÄS MER