Sökning: "collagen turnover markers"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden collagen turnover markers.

  1. 1. Molecular and clinical studies of cartilage and bone macromolecules in arthritis

    Författare :Bengt Månsson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Prognosis; Tissue damage; Bone markers; Cartilage markers; Rheumatoid arthritis; Psoriatic arthritis; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

    Sammanfattning : The pathogenesis of inflammatory arthritides include synovial inflammation and joint tissue destruction. Tissue destruction has traditionally been regarded a consequence of inflammation, but recent observations indicate that the processes are not always closely linked and may proceed uncoupled. LÄS MER

  3. 2. Female stress incontinence and uterovaginal prolapse : collagen turnover and hormone sensitivity in urogenital tissue

    Författare :Lena Edwall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Stress incontinence; urogenital tissue; collagen turnover markers; estradiol- 17beta; estrone; testosterone; uterovaginal prolapse; menopause;

    Sammanfattning : Background: Prevalence of both stress urinary incontinence (SUI) and uterovaginal prolapse (UP) is high and rising with age. Risk factors include multiparity, obesity, chronic obstructive lung disease and previous gynecological surgery. The underlying pathology is still unknown but may include defective connective tissue. LÄS MER

  4. 3. Back pain in primary care : aspects on treatment and the possible influence of oral contraceptives

    Författare :Ullacarin Wreje; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Low back pain; sacro-iliac joint; manipulation therapy; water; injections; relaxin; women; menstrual cycle; oral contraceptive; collagen metabolism;

    Sammanfattning : The general objectives of this thesis were to investigate back pain in a primary-care setting, and especially to study the effect of manual treatment on pelvic-joint dysfunction, the effect of sterile-water injections on chronic, myofascial pain and the possible influence of oral contraceptives (OC) on back pain in women in the fertile ages. The effect of a single intervention with manipulation mobilisation was compared with that of massage on pelvic-joint dysfunction with regard to sick-leave, consumption of analgesic, pain and joint mobility. LÄS MER

  5. 4. Joint disease biomarkers - discovery and application

    Författare :Dovilė Sinkevičiūtė; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osteoarthritis; Psoriatic arthritis; cartilage; Proteomics; Biomarkers; ELISA; Tissue culture; Extracellular matrix ECM ;

    Sammanfattning : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. LÄS MER

  7. 5. Hormone replacement therapy in rheumatoid arthritis

    Författare :Helena Forsblad d'Elia; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; randomised controlled trials; hormone replacement therapy; estrogen; osteoporosis; bone mineral density; bone remodelling; cartilage remodelling; cytokines; insulin-like growth factor 1;

    Sammanfattning : Rheumatoid arthritis (RA) is 2-3 times more frequent in women as compared to men. The peak incidence in women coincides with the years around the menopause and the course of RA is also influenced by events associated with hormonal alterations. LÄS MER