Sökning: "brain tissue"

Visar resultat 16 - 20 av 689 avhandlingar innehållade orden brain tissue.

1. 16. Proton Magnetic Resonance Spectroscopy in Brain Tumors - Clinical Applications

   Författare :Isabella Björkman-Burtscher; Lund Diagnostisk radiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiology; Clinical physics; Localization; Abscess; Brain; Tumor; Spectroscopy; Magnetic Resonance; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

   Sammanfattning : Aims: · to present a test phantom and test method for evaluation of proton magnetic resonance spectroscopy (1H-MRS) single volume localization techniques regarding signal contamination; · to describe the introduction of 1H-MRS in the daily routine of a standard MR-unit; · to evaluate the possibilities offered by 1H-MRS to improve preoperative diagnostic accuracy in patients scheduled for stereotactic biopsy of intracranial mass lesions; · to evaluate the possibilities offered by 1H-MRS to improve diagnostics and therapy control in patients with brain abscesses; · to test the hypothesis that 1H-MRS might be useful for differentiation of brain tumors, based on metabolic changes in tissue across brain lesions or surrounding tissue. Results and conclusions: · The test phantom and test method allow quality assessment with good reproducibility. LÄS MER

3. 17. Clusterin in brain and cerebrospinal fluidin Alzheimer s disease

   Författare :Anna-Maria Nilselid; Göteborgs universitet; []
   Nyckelord :Alzheimer s disease; clusterin; apolipoprotein J; SP-40; brain tissue; cerebrospinal fluid; glycosylation; biomarker; enzyme-linked immunosorbent assay;

   Sammanfattning : The apolipoprotein clusterin is suggested to be involved in the pathogenesis of Alzheimer¡¦s disease (AD). At the start of these studies, results had indicated that clusterin was elevated in AD brain, compared with controls. LÄS MER

4. 18. Label free analysis and spatial distribution of molecular lipids in brain tissue and cells using mass spectrometry imaging

   Författare :Amir Saeid Mohammadi; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry Imaging; Secondary Ion Mass Spectrometry Imaging; Matrix Assisted Laser desorption Ionization; Lipids; Brain tissue;

   Sammanfattning : Lipids are important inherent components in brain and cell membranes, which play significant biological roles in cell function. Identification and localization of specific biomolecules such as peptides and lipids within cellular membranes is currently a major challenge in metabolomics and biological studies. LÄS MER

5. 19. Inflammation-Induced Gene Expression in Brain and Adrenal Gland

   Författare :Linda Engström; Anders Blomqvist; Tomas Hökfelt; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; brain; adrenal gland; stress; lipopolysaccharide; interleukin-1; Neurobiology; Neurobiologi;

   Sammanfattning : The autonomic nervous system serves to maintain a constant inner environment, a process termed homeostasis. Thus, in response to the homeostatic challenge posed by infectious agents, the autonomic nervous system answers to signals from the immune system and elicits adaptive physiological and behavioral reactions. LÄS MER

7. 20. Apoptosis-related mechanisms in the immature brain after hypoxia-ischemia

   Författare :Xiaoyang Wang; Göteborgs universitet; []
   Nyckelord :hypoxia-ischemia; neonatal; caspase; ERK; XIAP; EPO; asialoEPO; brain;

   Sammanfattning : Aims: To characterize the activation of caspases-3 and extracellular signal-regulated kinase (ERK) in the neonatal brain after hypoxia-ischemia (HI) injury and evaluate the neuroprotective effect of X-linked inhibitor of apoptosis (XIAP) protein, erythropoietin (EPO) and the non-erythropoietic derivative asialoEPO. Methods: Seven-day-old rats or 9-day-old mice were subjected to HI. LÄS MER