Sökning: "bone development"

Visar resultat 21 - 25 av 519 avhandlingar innehållade orden bone development.

  1. 21. Laminins and Fibulins in Bone Marrow

    Författare :Yu-Chen Gu; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucocorticoids; integrin; Immunology; serology; Immunologi; serologi; transplantation; Cytology; oncology; Biokemi; Metabolism; Biochemistry; cancer; onkologi; cancerology; Cytologi; fibulin; laminin; bone marrow;

    Sammanfattning : Development of hematopoietic cells in bone marrow takes place in association with the hematopoietic microenvironment. Extracellular matrix (ECM) molecules and stromal cells in bone marrow provide a structural environment for hematopoietic cells, but they also directly influence proliferation, differentiation and migration of cells by signal transduction mediated by ligand binding to cell surface adhesion receptors. LÄS MER

  3. 22. Hyaluronan Derivatives and Injectable Gels for Tissue Engineering

    Författare :Kristoffer Bergman; Tim Bowden; Jöns Hilborn; Jeffrey Hubbell; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hyaluronan; Hydrogel; Tissue Engineering; Scaffold; Minimally invasive strategy; Bone morphogenetic protein; Hydroxyapatite; Bone; Cartilage; Tendon; Polymer chemistry; Polymerkemi;

    Sammanfattning : The present work describes the preparation of hyaluronan derivatives and hydrogels with potential use in tissue engineering applications. A potentially injectable hydrogel consisting of hyaluronan and collagen was successfully used to grow neurons in vitro by encapsulation of neural stem and progenitor cells. LÄS MER

  4. 23. The role of fibroblast growth factor-23 in chronic kidney disease-mineral and bone disorder

    Författare :Majd A. I. Mirza; Tobias Larsson; Tilman Drüeke; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FGF23; FGF-23; CKD; CKD-MBD; cardiovascular disease; vascular function; atherosclerosis; hypertrophy; LVMI; LVH; fractures; bone; fat mass; obesity; apolipoproteins; cholesterol; lipids; Kidney diseases; Njursjukdomar; Cardiovascular medicine; Kardiovaskulär medicin; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Fibroblast growth factor-23 (FGF23) was initially identified as the causative factor of autosomal dominant hypophosphatemic rickets. Further studies confirmed that FGF23 is predominantly expressed in the osteocytes and osteoblasts of bone and that circulating FGF23 acts on the kidney to inhibit renal phosphate reabsorption and 1,25(OH)2D3 hydroxylation. LÄS MER

  5. 24. The role of S100A4 protein as a regulator of inflammation and bone metabolism in experimental arthritis

    Författare :Li Bian; Göteborgs universitet; []
    Nyckelord :S100A4; arthritis; animal model; bone; inflammation;

    Sammanfattning : S100A4 belongs to the family of calcium-binding S100 proteins and modulates cell proliferation, cytoskeletal rearrangement, cell motility, and angiogenesis. Increased levels of S100A4 expression correlate with high incidence of metastasis of cancers. LÄS MER

  7. 25. Bone mass and physical activity

    Författare :Anna Nordström; Tommy Olsson; Peter Nordström; Heather McKay; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; physical activity; peak bone mineral density; males; fractures; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : Abstract Weak and osteoporotic bones in old age are an increasing cause of mortality and painful physical impairment of the elderly, especially in the western world. Bone mineral accrual during childhood and adolescence is thought to play a vital role in preventing osteoporosis. LÄS MER