Sökning: "biological networks"

Visar resultat 26 - 30 av 310 avhandlingar innehållade orden biological networks.

  1. 26. From Physicochemical Features to Interdependency Networks : A Monte Carlo Approach to Modeling HIV-1 Resistome and Post-translational Modifications

    Författare :Marcin Kierczak; Jan Komorowski; Anna Tramontano; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; HIV-1; resistome analysis; drug resistance; predicting PTMs; molecular interdependency networks; MCFS-ID; feature selection; interactome; machine-learning; rough sets; Bioinformatics; Bioinformatik; Computer Science; datavetenskap; Biology; with specialization in structural biology; biologi; med inriktning mot strukturbiologi;

    Sammanfattning : The availability of new technologies supplied life scientists with large amounts of experimental data. The data sets are large not only in terms of the number of observations, but also in terms of the number of recorded features. LÄS MER

  3. 27. Global regulatory factors that impact metabolic and lifestyle choices in Pseudomonas putida

    Författare :Lisa Wirebrand; Victoria Shingler; Matthew Francis; Carlos Balsalobre; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pseudomonas putida; c-di-GMP; motility; ppGpp; DksA; biofilm dispersal; transcriptional and translational regulation; dmp-system; phenol catabolism; carbon repression control; plasmid stability;

    Sammanfattning : Pseudomonas putida strains have a broad metabolic capacity and are innately resistant to many harmful substances – properties that make them of interest for a number of industrial and biotechnological application. They can rapidly adapt to changes in physico-chemical parameters in the soil and water environments they naturally inhabit. LÄS MER

  4. 28. Simplicity within Complexity : Understanding dynamics of cellular networks by model reduction

    Författare :Olivia Eriksson; Jesper Tegnér; Arne Elofsson; Yishao Zhou; Stefan Bornholdt; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; model reduction; cellular networks; dynamical modules; delayed piecewise linear; systems biology; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Cellular networks composed of interactions between genes, proteins and metabolites, determines the behavioural repertoire of the cell. Recent developments in high-throughput experimental techniques and computational methods allow static descriptions of these networks on a genome scale. LÄS MER

  5. 29. Computational Approaches to the Degeneration of Brain Networks and Other Complex Networks

    Författare :Simachew Abebe Mengiste; Jeanette Hällgren Kotaleski; Arvind Kumar; Ad Aertsen; Michelle Rudolph; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neurodegeneration; Synaptic pruning; Networks; Structure; Dynamics; Controllability;

    Sammanfattning : Networks are ubiquitous with several levels of complexity, configuration, hierarchy and function. Many micro- and macro-scale biological or non-biological interactions define complex systems. LÄS MER

  7. 30. Hidden patterns that matter : statistical methods for analysis of DNA and RNA data

    Författare :Therese Kellgren; Patrik Rydén; Sara Sjöstedt de Luna; Rebecka Jörnsten; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genome; Next-generation sequence; statistics; microarrays; bacteria; antibiotic resistance; inherited diseases; Co-expression networks; centralization within subgroups;

    Sammanfattning : Understanding how the genetic variations can affect characteristics and function of organisms can help researchers and medical doctors to detect genetic alterations that cause disease and reveal genes that causes antibiotic resistance. The opportunities and progress associated with such data come however with challenges related to statistical analysis. LÄS MER