Sökning: "Rebecka Jörnsten"
Hittade 5 avhandlingar innehållade orden Rebecka Jörnsten.
1. Data-driven quality management using explainable machine learning and adaptive control limits
Sammanfattning : In industrial applications, the objective of statistical quality management is to achieve quality guarantees through the efficient and effective application of statistical methods. Historically, quality management has been characterized by a systematic monitoring of critical quality characteristics, accompanied by manual and experience-based root cause analysis in case of an observed decline in quality. LÄS MER
2. Large scale integration and interactive exploration of cancer data – with applications to glioblastoma
Sammanfattning : Glioblastoma is the most common malignant brain tumor, with a median survival of approximately 15 months. The standard of care treatment consists of surgical resection followed by radiotherapy and chemotherapy, where chemotherapy only prolongs survival by approximately 3 months. LÄS MER
3. Hidden patterns that matter : statistical methods for analysis of DNA and RNA data
Sammanfattning : Understanding how the genetic variations can affect characteristics and function of organisms can help researchers and medical doctors to detect genetic alterations that cause disease and reveal genes that causes antibiotic resistance. The opportunities and progress associated with such data come however with challenges related to statistical analysis. LÄS MER
4. Normalization and analysis of high-dimensional genomics data
Sammanfattning : In the middle of the 1990’s the microarray technology was introduced. The technology allowed for genome wide analysis of gene expression in one experiment. Since its introduction similar high through-put methods have been developed in other fields of molecular biology. LÄS MER
5. Modeling glioblastoma growth patterns and their mechanistic origins
Sammanfattning : Glioblastoma (GBM) is the most common and aggressive primary brain cancer. GBM cells migrate away from the primary lesion and invade healthy brain tissue. The invading cells escape surgical resection, radiotherapy and develop resistance to chemotherapy. Consequently, despite treatment, recurrence is inevitable, and survival is only 14 months. LÄS MER