Sökning: "antimicrobial drug resistance"

Visar resultat 11 - 15 av 47 avhandlingar innehållade orden antimicrobial drug resistance.

  1. 11. Antimicrobial peptide therapy for tuberculosis infections

    Författare :Komal Umashankar Rao; Medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculosis; antimicrobial peptides; mode of action; nanoparticles; novel therapy; membrane active peptides;

    Sammanfattning : Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. LÄS MER

  3. 12. Individualized treatment and control of bacterial infections

    Författare :Hanna Woksepp; Thomas Schön; Anders Johansson; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; therapeutic drug monitoring; intensive care unit; β-lactam antibiotics; antimicrobial drug resistance; molecular typing; whole-genome sequencing; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : Infectious diseases cause substantial morbidity and mortality, exacerbated by increasing antibiotic resistance. In critically ill patients, recent studies indicate a substantial variability in β-lactam antibiotic levels when standardized dosing is applied. LÄS MER

  4. 13. Evolution of Antibiotic Resistance

    Författare :Franziska Pietsch; Diarmaid Hughes; Josep Casadesús; Uppsala universitet; []
    Nyckelord :ciprofloxacin; rifampicin; bacterial fitness; compensation; mutation rate; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : The emergence of antimicrobial resistance is a major global threat to modern medicine. The rapid dissemination of resistant pathogens and the associated loss of efficacy of many important drugs needs to be met with the development of new antibiotics and alternative treatment options. LÄS MER

  5. 14. Fluoroquinolone resistance in the environment and the human gut – Analysis of bacterial DNA sequences to explore the underlying genetic mechanisms

    Författare :Anna Johnning; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial resistance; Quinolones; Pollution; Next generation sequencing; Bioinformatics; Next generation sequencing;

    Sammanfattning : Fluoroquinolones (FQs) are synthetic, broad-spectrum antibiotics that target type II topoisomerases. High-level resistance is often caused by mutations in the target genes of FQs, especially in gyrA and parC. In contrast, plasmid-mediated resistance genes, such as qnr, often confer moderate levels of resistance. LÄS MER

  7. 15. Extended-spectrum beta-lactamase producing Enterobacteriaceae : aspects on detection, epidemiology and multi-drug resistance

    Författare :Maria Tärnberg; Lennart Nilsson; Hans-Jürg Monstein; Håkan Hanberger; Kristian Riesbeck; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Beta-lactam antibiotics are the largest and most commonly used group of antimicrobial agents in Sweden as well as world-wide. They show very good tolerability and many of the drugs can be administrated orally. LÄS MER